Evidence map›Paper›PMID 30603452›Full record

ArticleTissue engineering and regenerative medicine2016

Coculture effects on the osteogenic differentiation of human mesenchymal stromal cells.

Astghik Hayrapetyan, Soraya Surjandi, Evita E P J Lemsom, Marleen M M W Wolters, John A Jansen, Jeroen J J P van den Beucken

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering and regenerative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Frontiers in bioengineering and biotechnology · 2024
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Astghik Hayrapetyan1Department of Biomaterials, Radboudumc, Nijmegen, the Netherlands.
Soraya Surjandi1Department of Biomaterials, Radboudumc, Nijmegen, the Netherlands.
Evita E P J Lemsom1Department of Biomaterials, Radboudumc, Nijmegen, the Netherlands.
Marleen M M W Wolters1Department of Biomaterials, Radboudumc, Nijmegen, the Netherlands.
John A Jansen1Department of Biomaterials, Radboudumc, Nijmegen, the Netherlands.
Jeroen J J P van den Beucken1Department of Biomaterials, Radboudumc, Nijmegen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-based bone regeneration is generally pursued based on single cell type approaches, for which human adipose tissue-derived mesenchymal stromal cells (AT-MSCs) are frequently used, owing to their easy accessibility and relatively large yield. In view of multiple cell types involved in physiological bone regeneration, this study aimed to evaluate the osteogenic differentiation of AT-MSCs upon co-culture with endothelial cells or macrophages in a direct or indirect

Indexed as

Adipose tissue-derived mesenchymal stromal cellsCo-cultureEndothelial cellsMacrophagesOsteogenic differentiation

Identifiers

PMID30603452
PMCPMC6170873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.