Evidence map›Paper›PMID 30603436›Full record

ArticleTissue engineering and regenerative medicine2016

Efficient induction of neural precursor cells from fibroblasts using stromal cell-derived inducing activity.

Mi-Sun Lim, Sang-Mi Kim, Eun-Hye Lee, Chang-Hwan Park

Open access · bronzeAbstract read
In one paragraph

Article in Tissue engineering and regenerative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mi-Sun Lim1Hanyang Biomedical Research Institute, College of Medicine, Hanyang University, Seoul, Korea.
Sang-Mi Kim3Department of Biomedical Science, Graduate School, Hanyang University, Seoul, Korea.
Eun-Hye Lee3Department of Biomedical Science, Graduate School, Hanyang University, Seoul, Korea.
Chang-Hwan Park1Hanyang Biomedical Research Institute, College of Medicine, Hanyang University, Seoul, Korea.
Hanyang University · KRJeil Pharmaceutical (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The direct lineage conversion of fibroblasts into neuronal or neural precursor cells (NPCs) has become a hot issue in recent years as an attractive approach in the field of stem cell regenerative medicine. In this study, we adopted the stromal feeder co-culture method during the early conversion period to enhance conversion efficiency. Stromal cells are often used in directed differentiation of dopaminergic (DA) neurons from pluripotent stem cells. We co-cultured rat embryonic fibroblasts (REFs) on γ-irradiated sonic hedgehog-overexpressing MS5 stromal (MS5-SHH) cells after transduction with

Indexed as

Co-cultureDirect conversionDopaminergic neuronInduced neural precursor cellStromal cell

Identifiers

PMID30603436
PMCPMC6170833
OpenAlexW2525384749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.