Evidence map›Paper›PMID 30603422›Full record

ArticleTissue engineering and regenerative medicine2016

The efficacy and safety of Collagen-I and hypoxic conditions in urine-derived stem cell

So Young Chun, Hyun Tae Kim, Se Yun Kwon, Jeongshik Kim, Bum Soo Kim, Eun Sang Yoo, Tae Gyun Kwon

Abstract read
In one paragraph

Article in Tissue engineering and regenerative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Review
  11. Potency of Human Urine-Derived Stem Cells for Renal Lineage Differentiation.Tissue engineering and regenerative medicine · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

So Young Chun1Bio Medical Research Institute, Kyungpook National University Hospital, Daegu, Korea.
Hyun Tae Kim2Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea.
Se Yun Kwon3Department of Urology, College of Medicine, Dongguk University, Gyeongju, Korea.
Jeongshik KimDepartment of Pathology, Central Hospital, Ulsan, Korea.
Bum Soo Kim2Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea.
Eun Sang Yoo2Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea.
Tae Gyun Kwon2Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upper urinary tract-derived urine stem cells (USCs) are considered a valuable mesenchymal stem cell source for autologous cell therapy. However, the reported culture condition for USCs is not appropriate for large-quantity production, because cells can show limited replicativity, senescence, and undesirable differentiation during cultivation. These drawbacks led us to reconstitute a culture condition that mimics the natural stem cell niche. We selected extracellular matrix protein and oxygen tension to optimize the

Indexed as

Collagen-ICulture conditionHypoxiaMesenchymal stem cell sourceUrine-derived stem cells

Identifiers

PMID30603422
PMCPMC6171541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.