ArticleDiabetology international2017
Cognitive impairment in elderly patients with type 2 diabetes mellitus: prevalence and related clinical factors.
Article in Diabetology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.
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Who cites it
6 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Prevalence, risk factors, and early prediction of cognitive impairment in patients with diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Diabetic Retinopathy and Cognitive Dysfunction in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Epidemiological Associations and Clinical Implications.Journal of diabetes research · 2026Pooled it
- Cognitive impairment and associated factors among patients with diabetes mellitus in Africa: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Clinical characteristics of older adults with hypertension and unrecognized cognitive impairment.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Article
- Cognitive Impairment and Its Associated Risk Factors in the Elderly With Type 2 Diabetes Mellitus.Frontiers in psychiatry · 2021Article
- Impact of pharmacological treatment of diabetes mellitus on dementia risk: systematic review and meta-analysis.BMJ open diabetes research & care · 2018Article
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Authors and funding
4 authors.
Funding
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Abstract
aimDiabetes mellitus is reported to be a risk factor for dementia. We evaluated the cognitive function in elderly diabetic patients and estimated the prevalence of patients with cognitive impairment and looked for any related clinical factors. SUBJECTS AND
methodsUsing 281 elderly (65 years of age or older) Japanese patients with type 2 diabetes mellitus who were free of clinically evident cognitive impairment, we evaluated their cognitive function with the Mini Mental State Examination (MMSE).
resultsThe MMSE score of all the participants was 27.3 ± 2.4 with 31.3% of them being in the abnormal range (tentatively defined normal range as having an MMSE score of 27-30). Multiple regression analysis disclosed that fasting serum non-esterified fatty acid (NEFA), estimated glomerular filtration ratio (eGFR) and insulin treatment were significantly related factors for the MMSE score, in addition to age and schooling history, which are extremely strong factors.
conclusionsWe revealed that approximately one-third of elderly type 2 diabetic patients who were free of clinically evident cognitive impairment had impaired cognitive function, demonstrating that the MMSE score was significantly correlated with fasting NEFA level, renal function, insulin treatment, age and schooling history.
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