Evidence map›Paper›PMID 30603227›Full record

ReviewSurgical neurology international2018

Comprehensive review of neuromyelitis optica and clinical characteristics of neuromyelitis optica patients in Puerto Rico.

Sara Zarei, James Eggert, Laura Franqui-Dominguez, Yonatan Carl, Fernando Boria, Marina Stukova, Alessandro Avila, Cristina Rubi, Angel Chinea

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara ZareiSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
James EggertSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
Laura Franqui-DominguezSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
Yonatan CarlSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
Fernando BoriaSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
Marina StukovaSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
Alessandro AvilaSan Juan Bautista School of Medicine, Caguas, Puerto Rico, USA.
Cristina RubiCaribbean Neurological Center, Guaynabo, Puerto Rico, USA.
Angel ChineaCaribbean Neurological Center, Guaynabo, Puerto Rico, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromyelitis optica (NMO) is an immune-mediated inflammatory disorder of the central nervous system. It is characterized by concurrent inflammation and demyelination of the optic nerve (optic neuritis [ON]) and the spinal cord (myelitis). Multiple studies show variations in prevalence, clinical, and demographic features of NMO among different populations. In addition, ethnicity and race are known as important factors on disease phenotype and clinical outcomes. There are little data on information about NMO patients in underserved groups, including Puerto Rico (PR). In this research, we will provide a comprehensive overview of all aspects of NMO, including epidemiology, environmental risk factors, genetic factors, molecular mechanism, symptoms, comorbidities and clinical differentiation, diagnosis, treatment, its management, and prognosis. We will also evaluate the demographic features and clinical phenotype of NMO patients in PR. This will provide a better understanding of NMO and establish a basis of knowledge that can be used to improve care. Furthermore, this type of population-based study can distinguish the clinical features variation among NMO patients and will provide insight into the potential mechanisms that cause these variations.

Indexed as

AQP4 antibodiesmultiple sclerosismyelitisneuromyelitis opticaoptic neuritis

Identifiers

PMID30603227
PMCPMC6293609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.