Evidence map›Paper›PMID 30602980›Full record

ArticleAfrican health sciences2018

Seroprevalence of parvovirus B19 in blood donors: the risks and challenges of blood transfusion in Zambia in the era of HIV/AIDS at the Kitwe Central Hospital, blood bank.

Memory Chirambo-Kalolekesha, Trevor Kaile, Florence Mwaba, Victor Daka, Marah Simakando, Sumbukeni Kowa

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
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Article in African health sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Memory Chirambo-KalolekeshaUniversity of Zambia, School of Medicine, Department of Pathology and Microbiology.
Trevor KaileUniversity of Zambia, School of Medicine, Department of Pathology and Microbiology.
Florence MwabaUniversity of Zambia, School of Medicine, Department of Pathology and Microbiology.
Victor DakaUniversity of Zambia, School of Medicine, Department of Pathology and Microbiology.
Marah SimakandoUniversity of Zambia, School of Medicine, Department of Pathology and Microbiology.
Sumbukeni KowaUniversity of Zambia, School of Medicine, Department of Pathology and Microbiology.
University of Zambia · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman Parvovirus (B19V) is a small, single-stranded, non-enveloped DNA virus which is pathogenic to humans causing a wide array of clinical complications which include erythema infectiosum, aplastic crisis and hydrops foetalis. It is generally harmless in healthy individuals but may be life threatening in immunocompromised individuals such as patients with sickle cell disease, cancer, HIV and pregnant women. It has been shown to be transmissible by blood transfusion but donor screening for the virus is not yet mandatory in most sub-Saharan African countries including Zambia. MATERIALS AND

methodsThis was a cross-sectional study undertaken at the Kitwe Central Hospital, blood bank and Tropical Diseases Research Centre at Ndola Central Hospital. A total of 192 blood samples were screened for Ig M antibodies against parvovirus B19 by ELISA.

objectivesThe general objective of the study was to determine the seroprevalence of parvovirus B19 infections among healthy blood donors at the Kitwe Central Hospital blood bank. Specific Objectives were to detect parvovirus B19 Ig M antibodies in donor blood using serology and to analyse the age and sex distribution of parvovirus among blood donors.

resultsThe prevalence of parvovirus B19 Ig M in this study was 15.6%. The majority of the positive cases were in the age group 15-22 years (17.8%) but there was no statistical significance between occurrence of parvovirus and age ( p value=0.703). Prevalence in males was higher than in females that is 16.4% and 13.8%, respectively. The relationship between gender and parvovirus B19 occurrence was however not significant either (p value=0.516).

conclusionThis study showed a 15.6% prevalence rate of acute Parvovirus B19 infections in blood donors at the Kitwe Central Hospital, blood bank. Studies with larger sample sizes are needed to validate these results.

Indexed as

Blood DonorsBlood TransfusionAdultAntibodies, ViralBlood BanksCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansImmunoglobulin MMaleMiddle AgedParvoviridae InfectionsParvovirus B19, HumanSeroepidemiologic StudiesZambiaAntibodies, ViralImmunoglobulin Mblood bankblood transfusionHIV/AIDSKitwe Central HospitalParvovirus B19 in blood donorsZambia

Identifiers

PMID30602980
PMCPMC6307010
OpenAlexW2887320638

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.