Evidence map›Paper›PMID 30602930›Full record

ReviewProceedings. Mathematical, physical, and engineering sciences2018

Quantifying microbial chatter: scanning electrochemical microscopy as a tool to study interactions in biofilms.

Sophie E Darch, Dipankar Koley

Abstract readReview
In one paragraph

Review in Proceedings. Mathematical, physical, and engineering sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Triple-function carbon-based CaAnalytica chimica acta · 2024
    Article
  4. CytochromeProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. Review
  6. How to study biofilms: technological advancements in clinical biofilm research.Frontiers in cellular and infection microbiology · 2023
    Review
  7. Electrochemical Sensors Based on MoSAdvanced healthcare materials · 2022
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sophie E DarchSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID 0000-0003-2800-2844
Dipankar KoleyDepartment of Chemistry, Oregon State University, Corvallis, OR, USA.

Funding

Microenvironmental characterization and manipulation to prevent secondary cariesR01DE027999 · NIDCR · OREGON STATE UNIVERSITY · PI Dipankar Koley · 2018 to 2026
$3.6M
NIDCR NIH HHS R01 DE027999
6 · The paper itself

Abstract

Bacteria are often found in their natural habitats as spatially organized biofilm communities. While it is clear from recent work that the ability to organize into precise spatial structures is important for fitness of microbial communities, a significant gap exists in our understanding regarding the mechanisms bacteria use to adopt such physical distributions. Bacteria are highly social organisms that interact, and it is these interactions that have been proposed to be critical for establishing spatially structured communities. A primary means by which bacteria interact is via small, diffusible molecules including dedicated signals and metabolic by-products; however, quantitatively monitoring the production of these molecules in time and space with the micron-scale resolution required has been challenging. In this perspective, scanning electrochemical microscopy (SECM) is discussed as a powerful tool to study microbe-microbe interactions through the detection of small redox-active molecules. We highlight SECM as a means to quantify and spatially resolve the chemical mediators of bacterial interactions and begin to elucidate the mechanisms used by bacteria to regulate the emergent properties of biofilms.

Indexed as

aggregatebiofilmmicrobial interactionsscanning electrochemical microscopy

Identifiers

PMID30602930
PMCPMC6304031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.