Evidence map›Paper›PMID 30602535›Full record

ArticleScience translational medicine2019

A saliva-based rapid test to quantify the infectious subclinical malaria parasite reservoir.

Dingyin Tao, Brent McGill, Timothy Hamerly, Tamaki Kobayashi, Prachi Khare, Amanda Dziedzic, Tomasz Leski, Andrew Holtz, Bruce Shull, Anne E Jedlicka and 14 more

Open access · greenAbstract read
In one paragraph

Article in Science translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
  2. Article
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  4. Evaluation ofiScience · 2025
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  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Urine and Saliva: Relevant Specimens for Malaria Diagnosis?Diagnostics (Basel, Switzerland) · 2022
    Review
  14. Review
  15. Microscopic and submicroscopic infection byFrontiers in cellular and infection microbiology · 2022
    Article
  16. Article
  17. Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 10 institutions in 4 countries.

Dingyin TaoW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0001-6531-2740
Brent McGillW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0003-3177-3738
Timothy HamerlyW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0002-8670-3721
Tamaki KobayashiJohns Hopkins Malaria Research Institute, Baltimore, MD 21205, USA.
Prachi KhareEmerging Pathogens Institute and Department of Infectious Diseases & Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32611, USA.
Amanda DziedzicW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0002-2012-2035
Tomasz LeskiUnited States Naval Research Laboratory (NRL), Center for Biomolecular Science and Engineering, Washington, DC 20375, USA.ORCID 0000-0001-7688-9887
Andrew HoltzCollege of Science, George Mason University, Fairfax, VA 22030, USA.ORCID 0000-0002-4455-6014
Bruce ShullThermo Fisher Scientific, Fremont, CA 94538, USA.
Anne E JedlickaW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0003-3826-2973
Andrew WalzerThermo Fisher Scientific, Fremont, CA 94538, USA.ORCID 0000-0002-2148-1291
Paul D SloweyOasis Diagnostics, Vancouver, WA 98686, USA.ORCID 0000-0002-4472-3732
Christopher C SloweyOasis Diagnostics, Vancouver, WA 98686, USA.
Sandrine E NsangoLaboratoire de Recherche sur le Paludisme, Institut de Recherche pour le Développement-Organisation de Coordination et de Coopération pour la Lutte Contre les Grandes Endémies en Afrique Centrale (IRD-OCEAC), Yaoundé, Cameroon.
David A StengerUnited States Naval Research Laboratory (NRL), Center for Biomolecular Science and Engineering, Washington, DC 20375, USA.
Mike ChapondaTropical Disease Research Centre, Ndola, Zambia.ORCID 0000-0001-7847-9435
Modest MulengaTropical Disease Research Centre, Ndola, Zambia.
Kathryn H JacobsenCollege of Health and Human Services, George Mason University, Fairfax, VA 22030, USA.ORCID 0000-0002-4198-6246
David J SullivanW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Sadie J RyanEmerging Pathogens Institute and Department of Geography, College of Liberal Arts and Sciences, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-4308-6321
Rashid AnsumanaMercy Hospital Research Laboratory, Kulanda Town, Bo, Sierra Leone.
William J MossJohns Hopkins Malaria Research Institute, Baltimore, MD 21205, USA.
Isabelle MorlaisLaboratoire de Recherche sur le Paludisme, Institut de Recherche pour le Développement-Organisation de Coordination et de Coopération pour la Lutte Contre les Grandes Endémies en Afrique Centrale (IRD-OCEAC), Yaoundé, Cameroon.ORCID 0000-0002-2962-7670
Rhoel R DinglasanW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. rdinglasan@epi.ufl.edu.ORCID 0000-0001-5433-8179
Johns Hopkins University · USGeorge Mason University · USOasis Diagnostics (United States) · USThermo Fisher Scientific (United States) · USTropical Diseases Research Centre · ZMUnited States Naval Research Laboratory · USUniversity of Florida · USNjala University · SLOrganisation de Coordination pour la lutte contre les Endémies en Afrique Centrale · CMUniversity of Douala · CM

Funding

TransmissionU19AI089680 · NIAID · JOHNS HOPKINS UNIVERSITY · PI WILLIAM J MOSS · 2010 to 2026
$25.6M
NIAID NIH HHS U19 AI089680
6 · The paper itself

Abstract

A large proportion of ongoing malaria parasite transmission is attributed to low-density subclinical infections not readily detected by available rapid diagnostic tests (RDTs) or microscopy.

Indexed as

Asymptomatic InfectionsAdolescentAnimalsBiomarkersCameroonChildCross-Sectional StudiesDiagnostic Tests, RoutineDisease ReservoirsFemaleHumansLimit of DetectionMalaria, FalciparumParasitemiaParasitesProtozoan ProteinsBiomarkersProtozoan Proteinssexual stage specific protein, Plasmodium

Identifiers

PMID30602535
PMCPMC6441545
OpenAlexW2908218371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.