ArticleProceedings of the National Academy of Sciences of the United States of America2019
Interfacial fluid transport is a key to hydrogel bioadhesion.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- The Functional Role of Interface Tissue Engineering in Annulus Fibrosus Repair: Bridging Mechanisms of Hydrogel Integration with Regenerative Outcomes.ACS biomaterials science & engineering · 2020Pooled it
- Next-Generation Hydrogel Skin Adhesives: From Bioinspired Adhesion Chemistry to Regenerative Wound Interfaces.Advanced healthcare materials · 2026Review
- Robust Stitching Interface and Deep Learning Empowered Hydrogel Human-Machine Interface.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Sprayable Polymer Blends With Short-Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions.Advanced healthcare materials · 2026Article
- Article
- Covalently reactive microparticles imbibe blood to form fortified clots for rapid hemostasis and prevention of rebleeding.Nature communications · 2025Article
- A supramolecular hydrogel leveraging hierarchical multi-strength hydrogen-bonds hinged strategy achieving a striking adhesive-mechanical balance.Bioactive materials · 2025Article
- Inhibition of Angiogenesis and Effect on Inflammatory Bowel Disease of Ginsenoside Rg3-Loaded Thermosensitive Hydrogel.Pharmaceutics · 2024Article
- Introductory Review of Soft Implantable Bioelectronics Using Conductive and Functional Hydrogels and Hydrogel Nanocomposites.Gels (Basel, Switzerland) · 2024Review
- Highly efficient semiconductor modules making controllable parallel microchannels for non-compressible hemorrhages.Bioactive materials · 2024Article
- A 3D printable tissue adhesive.Nature communications · 2024Article
- Surface hydrophobization of hydrogels via interface dynamics-induced network reconfiguration.Nature communications · 2024Article
- Water-driven noninvasively detachable wet tissue adhesives for wound closure.Materials today. Bio · 2022Article
- Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage.Nature communications · 2022Article
- Coatings of hydroxyapatite-bioactive glass microparticles for adhesion to biological tissues.RSC advances · 2022Article
- Tissue Adhesives in Reconstructive and Aesthetic Surgery-Application of Silk Fibroin-Based Biomaterials.International journal of molecular sciences · 2022Review
- Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration.Journal of orthopaedic translation · 2022Article
- Polydopamine nanoparticles and hyaluronic acid hydrogels for mussel-inspired tissue adhesive nanocomposites.Biomaterials advances · 2022Article
- Diving beetle-like miniaturized plungers with reversible, rapid biofluid capturing for machine learning-based care of skin disease.Science advances · 2021Article
- Instant tough bioadhesive with triggerable benign detachment.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Attaching hydrogels to soft internal tissues is a key to the development of a number of biomedical devices. Nevertheless, the wet nature of hydrogels and tissues renders this adhesion most difficult to achieve and control. Here, we show that the transport of fluids across hydrogel-tissue interfaces plays a central role in adhesion. Using ex vivo peeling experiments on porcine liver, we characterized the adhesion between model hydrogel membranes and the liver capsule and parenchyma. By varying the contact time, the tissue hydration, and the swelling ratio of the hydrogel membrane, a transition between two peeling regimes is found: a lubricated regime where a liquid layer wets the interface, yielding low adhesion energies (0.1 J/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.