ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2019
Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 50 citations in OpenAlex.
- Prospective serial cardiovascular magnetic resonance imaging of immune checkpoint inhibitor myocarditis correlates with cardiovascular outcomes.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026Article
- Role of imaging techniques in monitoring atrial cardiomyopathy and atrial failure: a scientific statement.ESC heart failure · 2026Review
- High resolution, 3D isotropic late gadolinium enhanced imaging for the quantification of left atrial fibrosis and post-ablation scarring.European heart journal. Imaging methods and practice · 2026Article
- Predictors of atrial fibrillation recurrence following a successful electrical cardioversion - narrative review.Cardiology journal · 2026Review
- Magnetic resonance imaging based assessment of cardiac remodelling and tissue characteristics as predictor of atrial fibrillation in patients with moderate to severe rheumatic mitral valve disease.The international journal of cardiovascular imaging · 2025Article
- Atrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC.European journal of heart failure · 2025Article
- The left atrium in heart failure with preserved ejection fraction: What we know and what we do not know.Heart rhythm O2 · 2025Review
- Left atrial function and fibrosis in lifelong endurance athletes: a cardiac magnetic resonance imaging study.The international journal of cardiovascular imaging · 2025Article
- Novel Self-Calibrated Threshold-Free Probabilistic Fibrosis Signature Technique for 3D Late Gadolinium Enhancement MRI.IEEE transactions on bio-medical engineering · 2025Article
- Pathophysiology and clinical relevance of atrial myopathy.Basic research in cardiology · 2024Review
- Atrial fibrosis by cardiac MRI is a correlate for atrial stiffness in patients with atrial fibrillation.The international journal of cardiovascular imaging · 2024Article
- The Role of Cardiovascular Magnetic Resonance Imaging in Patients with Cardiac Arrhythmias.Reviews in cardiovascular medicine · 2023Review
- Association between Left Atrial Late Gadolinium Enhancement and Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis (MESA).Radiology. Cardiothoracic imaging · 2023Article
- Left Atrial Remodeling Following ST-Segment-Elevation Myocardial Infarction Correlates With Infarct Size and Age Older Than 70 Years.Journal of the American Heart Association · 2023Article
- Reverse remodeling of left atrium assessed by cardiovascular magnetic resonance feature tracking in hypertrophic obstructive cardiomyopathy after septal myectomy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Simultaneous Assessment of Left Atrial Fibrosis and Epicardial Adipose Tissue Using 3D Late Gadolinium Enhanced Dixon MRI.Journal of magnetic resonance imaging : JMRI · 2022Article
- Left Atrial Volumes and Function, and Long-Term Incidence of Ischemic Stroke in the General Population.Journal of the American Heart Association · 2022Article
- Left atrial structure and function are associated with cardiovascular outcomes independent of left ventricular measures: a UK Biobank CMR study.European heart journal. Cardiovascular Imaging · 2022Article
- Left atrial remodeling and the prognostic value of feature tracking derived left atrial strain in patients with light-chain amyloidosis: a cardiovascular magnetic resonance study.The international journal of cardiovascular imaging · 2022Article
- Atrial fibrillation and stroke: importance of left atrium as assessed by echocardiography.Journal of echocardiography · 2022Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundLeft atrial (LA) late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) imaging is indicative of fibrosis, and has been correlated with reduced LA function, increased LA volume, and poor procedural outcomes in cohorts with atrial fibrillation (AF). However, the role of LGE as a prognostic biomarker for arrhythmia in cardiac disease has not been examined.
methodsIn this study, we assessed LA LGE using a 3D LGE CMR sequence to examine its relationships with new onset atrial arrhythmia, and LA and left ventricular (LV) mechanical function.
resultsLA LGE images were acquired in 111 patients undergoing CMR imaging, including 66 patients with no prior history of an atrial arrhythmia. During the median follow-up of 2.7 years (interquartile range (IQR) 1.8-3.7 years), 15/66 (23%) of patients developed a new atrial arrhythmia. LA LGE ≥10% of LA myocardial volume was significantly associated with an increased rate of new-onset atrial arrhythmia, with a hazard ratio of 3.16 (95% CI 1.14-8.72), p = 0.026. There were significant relationships between LA LGE and both LA ejection fraction (r = - 0.39, p < 0.0005) and echocardiographic LV septal e' (r = - 0.24, p = 0.04) and septal E/e' (r = 0.31, p = 0.007).
conclusionsElevated LA LGE is associated with reduced LA function and reduced LV diastolic function. LA LGE is associated with new onset atrial arrhythmia during follow-up.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.