Evidence map›Paper›PMID 30602117›Full record

ArticleJournal of chemical information and modeling2019

Kinetic Analysis of Hepatic Metabolism Using Hyperpolarized Dihydroxyacetone.

Alexander Kirpich, Mukundan Ragavan, James A Bankson, Lauren M McIntyre, Matthew E Merritt

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Probing hepatic metabolism of [2-Magma (New York, N.Y.) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alexander KirpichDepartment of Biology , University of Florida , Gainesville , Florida 32611 , United States.
Mukundan RagavanDepartment of Biochemistry and Molecular Biology , University of Florida , Gainesville , Florida 32611 , United States.ORCID 0000-0001-8678-4229
James A BanksonDepartment of Imaging Physics , The University of Texas MD Anderson Cancer Center , Houston , Texas 77030 , United States.
Lauren M McIntyreSoutheast Center for Integrated Metabolomics , University of Florida , Gainesville , Florida 32611 , United States.
Matthew E MerrittSoutheast Center for Integrated Metabolomics , University of Florida , Gainesville , Florida 32611 , United States.ORCID 0000-0003-4617-9651
University of Florida · USThe University of Texas MD Anderson Cancer Center · US

Funding

Southeast Resource Center for Integrated Metabolomics (SECIM)U24DK097209 · NIDDK · UNIVERSITY OF FLORIDA · PI EDISON, ARTHUR S, YOST, RICHARD A. · 2013 to 2017
$9.2M
Multi-Site Development & Evaluation of a Quantitative 3D Hyperpolarized C-13 MRI Clinical Prostate Cancer ExamR01CA211150 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BANKSON, JAMES A · 2017 to 2021
$3.2M
Effects of maternal cortisol on perinatal cardiac metabolism and functionR01HD087306 · NICHD · UNIVERSITY OF FLORIDA · PI KELLER-WOOD, MAUREEN · 2017 to 2021
$2.3M
Metabolic Origins of Nonalcoholic SteatohepatitisR01DK112865 · NIDDK · UNIV OF MARYLAND, COLLEGE PARK · PI SUNNY, NISHANTH · 2017 to 2021
$1.8M
Imaging Hepatic Gluconeogenesis with Hyperpolarized DihydroxyacetoneR01DK105346 · NIDDK · UNIVERSITY OF FLORIDA · PI MERRITT, MATTHEW E · 2016 to 2020
$1.7M
NCI NIH HHS R01 CA211150NICHD NIH HHS R01 HD087306NIDDK NIH HHS R01 DK105346NIDDK NIH HHS R01 DK112865NIDDK NIH HHS U24 DK097209
6 · The paper itself

Abstract

Hyperpolarized carbon-13 magnetic resonance (HP-MR) is a new metabolic imaging method the does not use ionizing radiation. Due to the inherent chemical specificity of MR, not only tracer uptake but also downstream metabolism of the agent is detected in a straightforward manner. HP [2-

Indexed as

Models, BiologicalDihydroxyacetoneGlucoseKineticsLiverMagnetic Resonance SpectroscopyDihydroxyacetoneGlucose

Identifiers

PMID30602117
PMCPMC6533070
OpenAlexW2907138681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.