Evidence map›Paper›PMID 30601292›Full record

ArticleInvestigative radiology2019

Accelerated Segmented Diffusion-Weighted Prostate Imaging for Higher Resolution, Higher Geometric Fidelity, and Multi-b Perfusion Estimation.

Pelin Aksit Ciris, Jr-Yuan George Chiou, Daniel I Glazer, Tzu-Cheng Chao, Clare M Tempany-Afdhal, Bruno Madore, Stephan E Maier

Abstract read
In one paragraph

Article in Investigative radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. New prostate MRI techniques and sequences.Abdominal radiology (New York) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Pelin Aksit Ciris
Jr-Yuan George ChiouDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Daniel I GlazerDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Tzu-Cheng ChaoDepartment of Computer Science and Information Engineering, National Cheng Kung University, Tainan City, Taiwan.
Clare M Tempany-AfdhalDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Bruno MadoreDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Stephan E MaierDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Brigham and Women's Hospital · USAkdeniz University · TRHarvard University · USNational Cheng Kung University · TWUniversity of Gothenburg · SE

Funding

Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
Advancement and Validation of Prostate Diffusion and Spectroscopic MRIR01CA160902 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI MAIER, STEPHAN E · 2012 to 2017
$2.1M
Temperature monitoring in moving organs during thermal ablationR01CA149342 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI MADORE, BRUNO, PANYCH, LAWRENCE P · 2011 to 2015
$1.9M
Advanced Techniques for Rapid and Artifact-Resistant MR Diffusion ImagingR01EB010195 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI MADORE, BRUNO, MAIER, STEPHAN E · 2010 to 2013
$1.9M
NCI NIH HHS R01 CA149342NCI NIH HHS R01 CA160902NIBIB NIH HHS P41 EB015898NIBIB NIH HHS R01 EB010195
6 · The paper itself

Abstract

purposeThe aim of this study was to improve the geometric fidelity and spatial resolution of multi-b diffusion-weighted magnetic resonance imaging of the prostate. MATERIALS AND

methodsAn accelerated segmented diffusion imaging sequence was developed and evaluated in 25 patients undergoing multiparametric magnetic resonance imaging examinations of the prostate. A reduced field of view was acquired using an endorectal coil. The number of sampled diffusion weightings, or b-factors, was increased to allow estimation of tissue perfusion based on the intravoxel incoherent motion (IVIM) model. Apparent diffusion coefficients measured with the proposed segmented method were compared with those obtained with conventional single-shot echo-planar imaging (EPI).

resultsCompared with single-shot EPI, the segmented method resulted in faster acquisition with 2-fold improvement in spatial resolution and a greater than 3-fold improvement in geometric fidelity. Apparent diffusion coefficient values measured with the novel sequence demonstrated excellent agreement with those obtained from the conventional scan (R = 0.91 for bmax = 500 s/mm and R = 0.89 for bmax = 1400 s/mm). The IVIM perfusion fraction was 4.0% ± 2.7% for normal peripheral zone, 6.6% ± 3.6% for normal transition zone, and 4.4% ± 2.9% for suspected tumor lesions.

conclusionsThe proposed accelerated segmented prostate diffusion imaging sequence achieved improvements in both spatial resolution and geometric fidelity, along with concurrent quantification of IVIM perfusion.

Indexed as

AgedDiffusion Magnetic Resonance ImagingHumansImage Interpretation, Computer-AssistedMalePerfusionProstateProstatic NeoplasmsReproducibility of Results

Identifiers

PMID30601292
PMCPMC6402959
OpenAlexW2906770153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.