Evidence map›Paper›PMID 30600671›Full record

ArticleGut and liver2019

Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer.

Kentaro Yamashita, Ryo Suzuki, Toshiyuki Kubo, Kei Onodera, Tomoya Iida, Mayuko Saito, Yoshiaki Arimura, Takao Endo, Masanori Nojima, Hiroshi Nakase

Abstract read
In one paragraph

Article in Gut and liver, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Gastric Xanthoma: A Rare Case Report.Iranian journal of pathology · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. World journal of gastroenterology · 2021
    Review
  8. Gastric xanthoma is correlated with early gastric cancer of previouslyJGH open : an open access journal of gastroenterology and hepatology · 2021
    Article
  9. Gastric Xanthoma Associated with Gastric Cancer Development: An Updated Review.Canadian journal of gastroenterology & hepatology · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kentaro YamashitaDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.ORCID http://orcid.org/0000-0001-9003-9846
Ryo SuzukiDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.ORCID http://orcid.org/0000-0002-5339-2429
Toshiyuki KuboDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.ORCID http://orcid.org/0000-0002-0892-8298
Kei OnoderaDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.
Tomoya IidaDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.ORCID http://orcid.org/0000-0003-2842-8052
Mayuko SaitoDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.
Yoshiaki ArimuraDepartment of Gastroenterology, Otaru General Hospital, Otaru, Japan.ORCID http://orcid.org/0000-0002-3156-1500
Takao EndoDepartment of Gastroenterology, Sapporo Shirakaba-dai Hospital, Sapporo, Japan.ORCID http://orcid.org/0000-0001-7808-111X
Masanori NojimaCenter for Translational Research, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-8788-2522
Hiroshi NakaseDepartment of Gastroenterology and Hepatology, Sapporo Medical University, Sapporo, Japan.ORCID http://orcid.org/0000-0003-2848-6586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: Fundic gland polyps (FGPs), hyperplastic polyps (HPs), and xanthomas (XTs) are common benign gastric lesions that can be diagnosed by endoscopic appearance alone in most cases. The aim of this study was to evaluate associations between gastric cancer and these benign lesions. Methods: Two expert endoscopists reviewed a series of gastroscopy images. FGPs, HPs, and XTs were diagnosed by endoscopic appearance, whereas all gastric cancers were confirmed pathologically. Results: Of the 1,227 patients reviewed, 114 (9.3%) had a concurrent or past history of gastric cancer. The overall prevalences of FGPs, HPs and XTs were 9.4%, 6.3% and 14.2%, respectively. HPs and XTs coexisted in 1.6% of patients, whereas other combinations were rarer. XTs were observed in 39.3% and 11.5% of patients with and without gastric cancer, respectively (p<0.001). In contrast, no gastric cancer patients had FGPs, whereas 10.4% of patients without cancer had FGPs (p<0.001). The prevalence of HPs was similar between the two groups (8.8% and 6.0% of patients with and without cancer, respectively, p=0.29). Multivariate and Mantel-Haenszel analyses demonstrated that XTs were positively associated and FGPs were negatively associated with gastric cancer. Conclusions: XTs and FGPs might be useful as endoscopic risk indicators for monitoring gastric cancer.

Indexed as

GastroscopyAdolescentAdultAgedAged, 80 and overFemaleGastric FundusGastritis, AtrophicHelicobacter InfectionsHumansHyperplasiaJapanMaleMiddle AgedMultivariate AnalysisPolypsFundic gland polypsGastric xanthomasHyperplastic polypsStomach neoplasms

Identifiers

PMID30600671
PMCPMC6622560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.