SynthesisHuman brain mapping2019
Where is the "where" in the brain? A meta-analysis of neuroimaging studies on spatial cognition.
Synthesis in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Neurodevelopmental commonalities in cognitive control networks for mathematics and reading in meta-analysis of 3308 participants.Nature communications · 2025Pooled it
- Neural networks underlying magnitude perception: a specific meta-analysis of fMRI studies.Cerebral cortex (New York, N.Y. : 1991) · 2025Pooled it
- Gradient Organization of Space, Time, and Numbers in the Brain: A Meta-analysis of Neuroimaging Studies.Neuropsychology review · 2024Pooled it
- Common and specific activations supporting optic flow processing and navigation as revealed by a meta-analysis of neuroimaging studies.Brain structure & function · 2024Pooled it
- Neural substrates of spatial processing and navigation in blindness: An activation likelihood estimation meta-analysis.Frontiers in neuroscience · 2022Pooled it
- Egocentric and Allocentric Spatial Memory in Mild Cognitive Impairment with Real-World and Virtual Navigation Tasks: A Systematic Review.Journal of Alzheimer's disease : JAD · 2021Pooled it
- Where is the "where" in the brain? A meta-analysis of neuroimaging studies on spatial cognition.Human brain mapping · 2019Pooled it
- Properties of cross-modal occipital responses in early blindness: An ALE meta-analysis.NeuroImage. Clinical · 2019Pooled it
- Directed Communication in Theta and Alpha Networks Supports Content Handling in Working Memory.Human brain mapping · 2026Article
- Hand use predicts mental rotation ability in a sex-specific manner.Scientific reports · 2026Article
- Cortical dynamics are differentially associated with decision-making strategies in human wayfinding: An EEG study.Cognitive, affective & behavioral neuroscience · 2026Article
- Spatial memory retrieval under cueing in behavioral frontotemporal dementia and Alzheimer's disease.Dementia & neuropsychologia · 2026Article
- Article
- Digital Ergonomics of NavegApp, a Novel Serious Game for Spatial Cognition Assessment: Content Validity and Usability Study.JMIR serious games · 2025Article
- The Role of Cognitive Abilities in Project-Based Teaching: A Mixed Methods Study.Behavioral sciences (Basel, Switzerland) · 2025Article
- Simultaneous tACS-fMRI reveals state- and frequency-specific modulation of hippocampal-cortical functional connectivity.Communications psychology · 2025Article
- Brain activity during acquisition of long visuospatial sequences.Frontiers in cognition · 2025Article
- Functional coupling of the lateral prefrontal cortex and the default mode network predicts performance in mental rotation.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Gray matter volume increase in the retrosplenial/posterior cingulate cortices of blind soccer players.Frontiers in neuroscience · 2025Article
- The cingulum: anatomy, connectivity and what goes beyond.Brain communications · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spatial representations are processed in the service of several different cognitive functions. The present study capitalizes on the Activation Likelihood Estimation (ALE) method of meta-analysis to identify: (a) the shared neural activations among spatial functions to reveal the "core" network of spatial processing; (b) the specific neural activations associated with each of these functions. Following PRISMA guidelines, a total of 133 fMRI and PET studies were included in the meta-analysis. The overall analysis showed that the core network of spatial processing comprises regions that are symmetrically distributed on both hemispheres and that include dorsal frontoparietal regions, presupplementary motor area, anterior insula, and frontal operculum. The specific analyses revealed the brain regions that are selectively recruited for each spatial function, such as the right temporoparietal junction for shift of spatial attention, the right parahippocampal gyrus, and the retrosplenial cortex for navigation and spatial long-term memory. The findings are integrated within a systematic review of the neuroimaging literature and a new neurocognitive model of spatial cognition is proposed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.