Evidence map›Paper›PMID 30600443›Full record

ArticleThe journal of physiological sciences : JPS2019

Asparagine-linked glycosylation modifies voltage-dependent gating properties of Ca

Yangong Liu, Pu Wang, Fangfang Ma, Mingqi Zheng, Gang Liu, Shinichiro Kume, Tatsuki Kurokawa, Katsushige Ono

Open access · goldAbstract read
In one paragraph

Article in The journal of physiological sciences : JPS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Monoterpene Indole Alkaloids with CaMolecules (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yangong LiuDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Pu WangDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Fangfang MaDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Mingqi ZhengDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Gang LiuDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Shinichiro KumeDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan.
Tatsuki KurokawaDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan.
Katsushige OnoDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan. ono@oita-u.ac.jp.ORCID http://orcid.org/0000-0001-7949-1823
Hebei Medical University · CNOita University · JP

Funding

KAKEN 25460292
6 · The paper itself

Abstract

T-type channels are low-voltage-activated channels that play a role in the cardiovascular system particularly for pacemaker activity. Glycosylation is one of the most prevalent post-translational modifications in protein. Among various glycosylation types, the most common one is asparagine-linked (N-linked) glycosylation. The aim of this study was to elucidate the roles of N-linked glycosylation for the gating properties of the Ca

Indexed as

AsparagineCalcium Channels, T-TypeCell LineCell MembraneGlycosylationHEK293 CellsHumansIon Channel GatingKineticsMembrane PotentialsTunicamycinAsparagineCACNA1G protein, humanCalcium Channels, T-TypeTunicamycinCaV3.1GlycosylationT-type Ca2+ channelTunicamycinα1G channel

Identifiers

PMID30600443
PMCPMC10717069
OpenAlexW2907943606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.