Evidence map›Paper›PMID 30600386›Full record

ArticleAbdominal radiology (New York)2019

Magnetic resonance elastography SE-EPI vs GRE sequences at 3T in a pediatric population with liver disease.

Juan S Calle-Toro, Suraj D Serai, Erum A Hartung, David J Goldberg, Bradley D Bolster, Kassa Darge, Sudha A Anupindi

Abstract read
In one paragraph

Article in Abdominal radiology (New York), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

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  14. Review
  15. Imaging Modalities in Pediatric NAFLD.Clinical liver disease · 2021
    Review
  16. Article
  17. MR Elastography of the Abdomen: Experimental Protocols.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  18. MR Elastography of the Abdomen: Basic Concepts.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Juan S Calle-ToroDivision of Body Imaging, Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, USA.
Suraj D SeraiDivision of Body Imaging, Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, USA. serais@email.chop.edu.
Erum A HartungDivision of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
David J GoldbergDivision of Cardiology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Bradley D BolsterSiemens Healthineers, Malvern, PA, USA.
Kassa DargeDivision of Body Imaging, Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, USA.
Sudha A AnupindiDivision of Body Imaging, Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA, USA.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · USSiemens Healthcare (United States) · US

Funding

Novel Imaging Biomarkers in Autosomal Recessive Polycystic Kidney DiseaseK23DK109203 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI HARTUNG, ERUM AFTAB · 2016 to 2019
$728k
NIDDK NIH HHS K23 DK109203
6 · The paper itself

Abstract

purposeThe goal of our study is to compare hepatic stiffness measures using gradient-recalled echo (GRE) versus spin-echo echo planar imaging (SE-EPI)-based MR Elastography (MRE) at 3T used to measure hepatic stiffness in a patients with suspected liver diseases. MATERIALS AND

methodsThis retrospective study included 52 patients with liver disease who underwent a 3T MRE exam including both an investigational SE-EPI-based technique and a product GRE-based technique. Regions of interest (ROI) were placed on the elastograms to measure elastography-derived liver stiffness as well as the area included within the ROIs. The mean liver stiffness values and area of ROIs were compared.

resultsThe mean liver stiffness was 3.72 kilopascal (kPa) ± 1.29 using GRE MRE and 3.78 kPa ± 1.13 using SE-EPI MRE. Measurement of liver stiffness showed excellent agreement between the two pulse sequences with a mean bias of - 0.1 kPa (range - 1.8 to 1.7 kPa) between sequences. The mean measurable ROI area was higher with SE-EPI (313.8 cm

conclusionsOur data shows excellent agreement of measured liver stiffness between GRE and SE-EPI-based sequences at 3T. Our results show the advantage of a SE-EPI MRE sequence in terms of image quality, ROI size and acquisition time with equivalent liver stiffness measurements as compared to GRE-MRE sequence.

Indexed as

AdolescentAdultChildEcho-Planar ImagingElasticity Imaging TechniquesFemaleHumansLiverLiver DiseasesMagnetic Resonance ImagingMaleReproducibility of ResultsRetrospective StudiesYoung AdultFibrosisGRE MRELiverMagnetic resonance imagingMR elastographySE-EPI MRE

Identifiers

PMID30600386
PMCPMC6484437
OpenAlexW2908078805

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.