Evidence map›Paper›PMID 30599666›Full record

ArticleThe Journal of the Acoustical Society of America2018

Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?

Rene L Utianski, Hugo Botha, Joseph R Duffy, Heather M Clark, Peter R Martin, Alissa M Butts, Mary M Machulda, Jennifer L Whitwell, Keith A Josephs

Abstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rene L UtianskiDepartment of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Hugo BothaDepartment of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Joseph R DuffyDepartment of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Heather M ClarkDepartment of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Peter R MartinDepartment of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota 55902, USA.
Alissa M ButtsDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Mary M MachuldaDepartment of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Jennifer L WhitwellDepartment of Radiology, Mayo Clinic, Rochester, Minnesota 55902, USA.
Keith A JosephsDepartment of Neurology, Mayo Clinic, Rochester, Minnesota 55902, USA.

Funding

Longitudinal multi-modality imaging in progressive apraxia of speech (Diversity Supplement)R01DC012519 · NIDCD · MAYO CLINIC ROCHESTER · PI Jennifer Louise Whitwell · 2013 to 2026
$7.2M
PIB PET Scanning in Speech and Language Based DementiasR01DC010367 · NIDCD · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2010 to 2014
$1.7M
Assessment of hyperphosphorylated tau PET binding in primary progressive aphasiaR21NS094684 · NINDS · MAYO CLINIC ROCHESTER · PI JOSEPHS, KEITH A · 2016 to 2017
$417k
NIDCD NIH HHS R01 DC010367NIDCD NIH HHS R01 DC012519NINDS NIH HHS R21 NS094684
6 · The paper itself

Abstract

This study examined the rate of producing alternating motion rates, sequential motion rates (SMRs), and repeated words in 27 individuals with the semantic variant of Primary Progressive Aphasia (svPPA). Only the rate of producing SMRs was significantly elevated in svPPA compared to controls. This may be associated with concomitant neuropsychiatric symptoms in svPPA, as correlation analysis showed a relationship between increased SMR rate and the Neuropsychiatric Inventory Questionnaire, which documented anxiety and disinhibition. Future studies will assess these findings in a larger cohort and work to better understand if this phenomenon is a manifestation of behavioral and/or motor changes.

Indexed as

SemanticsAgedAphasia, Primary ProgressiveFemaleHumansMaleMiddle AgedSpeech

Identifiers

PMID30599666
PMCPMC6296908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.