ArticleAnnals of pediatric endocrinology & metabolism2018
Early-life exposure to endocrine disrupting chemicals associates with childhood obesity.
Article in Annals of pediatric endocrinology & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Sensitive periods to social adversity in immune and metabolic development: A systematic review.Psychoneuroendocrinology · 2025Pooled it
- Prenatal and childhood exposure to per-/polyfluoroalkyl substances (PFASs) and its associations with childhood overweight and/or obesity: a systematic review with meta-analyses.Environmental health : a global access science source · 2023Pooled it
- Prenatal exposure to nonpersistent endocrine disruptors and early childhood BMI: single pollutant and mixture analyses from the ECHO Program.Pediatric research · 2026Article
- Modern Determinants of Earlier Menarche and Mental Health: A Translational Review for Clinicians.Children (Basel, Switzerland) · 2026Review
- Early-Life Exposure to Organic Chemical Pollutants as Assessed in Primary Teeth and Cardiometabolic Risk in Mexican American Children: A Pilot Study.International journal of environmental research and public health · 2025Article
- The Effects of Maternal Endocrinopathies and Exposure to Endocrine Disruptors During Pregnancy on the Fetus and Newborn.Biomedicines · 2025Review
- The synergic impact of decellularized testis scaffold and extracellular vesicles derived from human semen on spermatogonial stem cell survival and differentiation.Biomedical engineering online · 2025Article
- Prenatal polycyclic aromatic hydrocarbons exposure and child growth and adiposity: A longitudinal study.Environmental research · 2025Article
- Article
- Effects of Bisphenol A on the Risk of Developing Obesity.Nutrients · 2024Review
- Maternal phthalate exposure and BMI trajectory in children-an 18-year birth cohort follow-up study.Journal of exposure science & environmental epidemiology · 2024Article
- Unravelling the Influence of Endocrine-Disrupting Chemicals on Obesity Pathophysiology Pathways.Advances in experimental medicine and biology · 2024Review
- Supporting early childhood routines to promote cardiovascular health across the life course.Current problems in pediatric and adolescent health care · 2023Article
- Nutrition, obesity, and dental development in young adolescents in Chicago.American journal of human biology : the official journal of the Human Biology Council · 2022Article
- Bisphenol A (BPA) Leading to Obesity and Cardiovascular Complications: A Compilation of Current In Vivo Study.International journal of molecular sciences · 2022Review
- The Role of the Bisphenol A in Diabetes and Obesity.Biomedicines · 2021Review
- Machine Learning for Investigation on Endocrine-Disrupting Chemicals with Gestational Age and Delivery Time in a Longitudinal Cohort.Research (Washington, D.C.) · 2021Article
- Real-world data reveal unmet clinical needs in insulin treatment in Asian people with type 2 diabetes: the Joint Asia Diabetes Evaluation (JADE) Register.Diabetes, obesity & metabolism · 2020Article
- Risk Assessment of Cosmetics Using Triclosan on Future Generation's Germ Cell Maturation via Lactating Mother Rats.International journal of environmental research and public health · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing prevalence of childhood obesity poses threats to the global health burden. Because this rising prevalence cannot be fully explained by traditional risk factors such as unhealthy diet and physical inactivity, early-life exposure to endocrine disrupting chemicals (EDCs) is recognized as emerging novel risk factors for childhood obesity. EDCs can disrupt the hormone-mediated metabolic pathways, affect children's growth and mediate the development of childhood obesity. Many organic pollutants are recently classified to be EDCs. In this review, we summarized the epidemiological and laboratory evidence related to EDCs and childhood obesity, and discussed the possible mechanisms underpinning childhood obesity and early-life exposure to non-persistent organic pollutants (phthalates, bisphenol A, triclosan) and persistent organic pollutants (dichlorodiphenyltrichloroethane, polychlorinated biphenyls, polybrominated diphenyl ethers, per- and polyfluoroalkyl substances). Understanding the relationship between EDCs and childhood obesity helps to raise public awareness and formulate public health policy to protect the youth from exposure to the harmful effects of EDCs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.