Evidence map›Paper›PMID 30599070›Full record

ArticleProgress in biomaterials2019

Study of physico-chemical properties and in vitro antimicrobial activity of hydroxyapatites obtained from bone calcination.

Cássio M Resmim, Mariane Dalpasquale, Nilce I C Vielmo, Filipe Q Mariani, Juan C Villalba, Fauze J Anaissi, Mirian M Caetano, Marcelo M Tusi

Open access · hybridAbstract read
In one paragraph

Article in Progress in biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Low Percent Copper Doping Limits Bacterial Adhesion on Fluorapatite-Based Bone Scaffolds.Journal of biomedical materials research. Part B, Applied biomaterials · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cássio M ResmimUniversidade Regional Integrada do Alto Uruguai e das Missões-URI, Av. Batista Bonoto Sobrinho, 733, São Vicente, Santiago, RS, 97700-000, Brazil.
Mariane DalpasqualeUniversidade Estadual do Centro-Oeste-UNICENTRO, R. Simeão Varela de Sá, 03, Vila Carli, Guarapuava, PR, 85040-080, Brazil.
Nilce I C VielmoUniversidade Regional Integrada do Alto Uruguai e das Missões-URI, Av. Batista Bonoto Sobrinho, 733, São Vicente, Santiago, RS, 97700-000, Brazil.
Filipe Q MarianiFaculdade Campo Real, R. Comendador Norberto, 1299, Santa Cruz, Guarapuava, PR, 85040-080, Brazil.
Juan C VillalbaUniversidade Estadual do Centro-Oeste-UNICENTRO, R. Simeão Varela de Sá, 03, Vila Carli, Guarapuava, PR, 85040-080, Brazil.
Fauze J AnaissiUniversidade Estadual do Centro-Oeste-UNICENTRO, R. Simeão Varela de Sá, 03, Vila Carli, Guarapuava, PR, 85040-080, Brazil.
Mirian M CaetanoUniversidade Regional Integrada do Alto Uruguai e das Missões-URI, Av. Batista Bonoto Sobrinho, 733, São Vicente, Santiago, RS, 97700-000, Brazil.
Marcelo M TusiUniversidade Regional Integrada do Alto Uruguai e das Missões-URI, Av. Batista Bonoto Sobrinho, 733, São Vicente, Santiago, RS, 97700-000, Brazil. mmtusi@urisantiago.br.
Universidade Regional Integrada do Alto Uruguai e das Missões · BRUniversidade Estadual do Centro-Oeste · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxyapatite was obtained by bone calcinations. To study the calcination process, bovine and porcine bones were first autoclaved to remove fat and other non-bone tissues. They were then heated in an alumina pan in an oxidizing atmosphere of air, where simultaneous thermal analysis curves were recorded. To prepare the hydroxyapatites, bone samples were calcined at 850 °C and 1000 °C using a muffle furnace for 1 h. The obtained materials were powdered using mortar and pestle, and sifted in a sieve (60 mesh) without any additional purification or chemical treatment. The materials obtained were characterized by energy-dispersive X-ray spectroscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. The antimicrobial properties of these materials were determined through direct contact tests against Staphylococcus aureus. The natural hydroxyapatites obtained by bone calcination inhibited S. aureus growth, with the material obtained by calcination of bovine bones at 1000 °C, showing the best antimicrobial activity. These results indicated that bone wastes can be used to obtain hydroxyapatites with antimicrobial activity.

Indexed as

BiomaterialBovineHydroxyapatitePorcineStaphylococcus aureus

Identifiers

PMID30599070
PMCPMC6425081
OpenAlexW2907758608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.