Evidence map›Paper›PMID 30599004›Full record

ArticleJournal of immunology research2018

Food-Grade Saponin Extract as an Emulsifier and Immunostimulant in Emulsion-Based Subunit Vaccine for Pigs.

Yulia Burakova, Rachel Madera, Lihua Wang, Sterling Buist, Karen Lleellish, John R Schlup, Jishu Shi

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Triterpenoid Saponins from Washnut (Plants (Basel, Switzerland) · 2022
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yulia BurakovaDepartment of Anatomy and Physiology, College of Veterinary Science, Kansas State University, 228 Coles Hall, 1620 Denison Ave, Manhattan, KS 66506, USA.
Rachel MaderaDepartment of Anatomy and Physiology, College of Veterinary Science, Kansas State University, 228 Coles Hall, 1620 Denison Ave, Manhattan, KS 66506, USA.
Lihua WangDepartment of Anatomy and Physiology, College of Veterinary Science, Kansas State University, 228 Coles Hall, 1620 Denison Ave, Manhattan, KS 66506, USA.
Sterling BuistDepartment of Anatomy and Physiology, College of Veterinary Science, Kansas State University, 228 Coles Hall, 1620 Denison Ave, Manhattan, KS 66506, USA.
Karen LleellishDepartment of Anatomy and Physiology, College of Veterinary Science, Kansas State University, 228 Coles Hall, 1620 Denison Ave, Manhattan, KS 66506, USA.
John R SchlupDepartment of Chemical Engineering, College of Engineering, Kansas State University, 1005 Durland Hall, 1701A Platt St, Manhattan, KS 66506, USA.
Jishu ShiDepartment of Anatomy and Physiology, College of Veterinary Science, Kansas State University, 228 Coles Hall, 1620 Denison Ave, Manhattan, KS 66506, USA.ORCID 0000-0002-7177-9280
Kansas State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subunit vaccines consisting of highly purified antigens require the presence of adjuvants to create effective and long-lasting protective immunity. Advances on adjuvant research include designing combination adjuvants which incorporate two or more adjuvants to enhance vaccine efficacy. Previously, an oil-in-water emulsion adjuvant (OW-14) composed of mineral oil and an inexpensive gum Arabic emulsifier has been reported demonstrating enhanced and robust immune responses when used as an adjuvant in swine subunit vaccines. This study presents a modified version of OW-14 prepared with food-grade

Indexed as

Adjuvants, ImmunologicAnimalsAntibodies, NeutralizingAntibodies, ViralClassical Swine FeverClassical Swine Fever VirusEmulsifying AgentsHumansPlant ExtractsQuillajaSaponinsSwineVaccinationVaccines, SubunitViral Envelope ProteinsViral VaccinesAdjuvants, ImmunologicAntibodies, NeutralizingAntibodies, ViralEmulsifying Agentsglycoprotein E2, classical swine fever virusPlant ExtractsSaponinsVaccines, SubunitViral Envelope ProteinsViral Vaccines

Identifiers

PMID30599004
PMCPMC6288570
OpenAlexW2902697759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.