ArticleInternational journal of applied & basic medical research
Gestational Toxicity of Calabash Chalk (Nzu) in Wistar Rats.
Article in International journal of applied & basic medical research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
objectiveCalabash chalk (Nzu) is a geophagic material, consumed by many pregnant women and breastfeeding mothers as remedy for morning sickness in most African countries. The present study aims to evaluate the impact of Calabash chalk consumption in pregnant Wistar rats. MATERIALS AND
methodsMedian lethal dose of Calabash chalk was initially determined in Wistar rats to be >5000 mg/kg po using Lorke's method. Thereafter, 24 pregnant Wistar rats were divided randomly into 3 groups (
resultsCalabash chalk exposure inhibited maternal weight gain. Uterine implantations were absent in 85% of Calabash chalk exposed rats, and the number of implantation sites were decreased (
conclusionThe results suggest that Calabash chalk has a negative relationship with maternal health and pregnancy outcome.
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