ArticleWorld journal of emergency medicine2019
Comparison between intravenous morphine versus fentanyl in acute pain relief in drug abusers with acute limb traumatic injury.
Article in World journal of emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- The safety and efficacy of perioperative nefopam for analgesia in spine surgery: A systematic review and meta-analysis of randomised controlled trials.Neurosurgical review · 2026Pooled it
- Pooled it
- Efficacy of opioids for traumatic pain in the emergency department: a systematic review and Bayesian network meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Clinical efficacy of acupuncture for pain relief from renal colic: A meta-analysis and trial sequence analysis.Frontiers in medicine · 2022Pooled it
- A non-inferiority randomized controlled trial comparing nebulized fentanyl and intravenous morphine for acute pain management in the emergency department.BMC emergency medicine · 2026Trial
- Trial
- Regional analgesia using ultrasound-guided intermediate cervical plexus block versus cervical erector spinae block for anterior cervical spine surgery: a randomized trial.BMC anesthesiology · 2024Trial
- Comparison of the ED50 of Ciprofol Combined With or Without Fentanyl for Laryngeal Mask Airway Insertion in Children: A Prospective, Randomized, Open-Label, Dose-Response Trial.Drug design, development and therapy · 2024Trial
- Effects of dexamethasone on catheter-related bladder discomfort and emergence agitation: a prospective, randomized, controlled trial.Korean journal of anesthesiology · 2022Trial
- Article
- Pain relief for femur fractures using Fascia Iliaca Block and IV fentanyl.Bioinformation · 2025Article
- Does IV fentanyl, frequently used in emergency departments, change QTBMC anesthesiology · 2024Observational
- Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal.Communications medicine · 2024Article
- Comparison of postoperative analgesia and side effects in pediatric laparoscopic surgery with morphine and nalbuphine.iScience · 2024Article
- Pharmacological mechanisms underlying the efficacy of antibodies generated by a vaccine to treat oxycodone use disorder.Neuropharmacology · 2021Article
- A case of rhabdomyolysis with compartment syndrome in the right upper extremity.World journal of emergency medicine · 2020Article
- The Effect of Intraoperative Methadone Compared to Morphine on Postsurgical Pain: A Meta-Analysis of Randomized Controlled Trials.Anesthesiology research and practice · 2020Review
- A Comparative Study between Propofol-fentanyl versus Propofol-suxamethonium for Ease of Endotracheal Intubation in Children.Journal of the West African College of SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRapid and effective pain relief in acute traumatic limb injuries (ATLI) is one of the most important roles of emergency physicians. In these situations, opioid addiction is an important concern because of the dependency on opioids. The study aims to compare the effectiveness of intravenous (IV) fentanyl versus morphine in reducing pain in patients with opioid addiction who suffered from ATLI.
methodsIn this double-blind randomized clinical trial, 307 patients with ATLI, who presented to the emergency department (ED) from February 2016 to April 2016, were randomly divided into two groups. One group (152 patients) received 0.1 mg/kg IV morphine. The other group (155 patients) received 1 mcg/kg IV fentanyl. Patients' demographic data, pain score at specific intervals, vital signs, side effects, satisfaction and the need for rescue analgesia were recorded.
resultsEight patients in the morphine group and five patients in the fentanyl group were excluded. Pain score in the fentanyl group had a significant decrease at 5-minute follow-up (
conclusionFentanyl might be an effective and safe drug in opioid addicts suffering from ATLI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.