Evidence map›Paper›PMID 30598687›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

JYYS Granule Mitigates Renal Injury in Clinic and in Spontaneously Hypertensive Rats by Inhibiting NF-

Dong Yan, Bowen Yue, Muyan Qian, Lili Zhao, Zihan Zhang, Hui Qian, Shihai Yan, Yuliang Qian, Zhuyuan Fang

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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  8. Annals of translational medicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dong YanJiangsu Province Hospital of TCM, Affiliated Hospital of Nanjing University of TCM, Nanjing, China.
Bowen YueNanjing University of TCM, Nanjing, China.
Muyan QianNanjing Foreign Language School, Nanjing, China.
Lili ZhaoNanjing University of TCM, Nanjing, China.
Zihan ZhangNanjing University of TCM, Nanjing, China.
Hui QianNanjing University of TCM, Nanjing, China.
Shihai YanJiangsu Province Hospital of TCM, Affiliated Hospital of Nanjing University of TCM, Nanjing, China.
Yuliang QianJiangsu Province Hospital of TCM, Affiliated Hospital of Nanjing University of TCM, Nanjing, China.ORCID 0000-0001-8337-1277
Zhuyuan FangJiangsu Province Hospital of TCM, Affiliated Hospital of Nanjing University of TCM, Nanjing, China.ORCID 0000-0003-1792-6937
Nanjing Traditional Chinese Medicine Hospital · CNJiangsu Province Hospital · CNNanjing Foreign Language School · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertensive renal damage is a chronic and life-threatening kidney disease all over the world. The traditional Chinese medicine Jiang Ya Yi Shen (JYYS) granule has been a perfect drug for patients with hypertensive renal injury in clinic for 20 years in China. However, the molecular mechanism of JYYS granule remains unknown in treatment of this disease.

methodsThe clinic data were from this study's patients. The clinical symptoms of patients were indicated by (N-Acetyl-

resultsJYYS significantly improved the clinic symptoms of patients with hypertensive nephropathy by downregulating NAG, Alb, and

conclusionJYYS is a promising prescription of Chinese medicine for patients with hypertension and hypertensive renal damage.

Identifiers

PMID30598687
PMCPMC6287156
OpenAlexW2902870455

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.