Evidence map›Paper›PMID 30598683›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2018

Traditional Chinese Medicine in Neuroprotection after Brain Insults with Special Reference to Radioprotection.

Xiao Chun Peng, Jiang Rong Huang, Si Wei Wang, Lian Liu, Zhen Zhen Liu, Gautam Sethi, Bo Xu Ren, Feng Ru Tang

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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  11. [Vitamin E reduces radiation injury of hippocampal neurons in mice by inhibiting ferroptosis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao Chun PengMedical School of Yangtze University, Jingzhou 434000, China.
Jiang Rong HuangMedical School of Yangtze University, Jingzhou 434000, China.
Si Wei WangMedical School of Yangtze University, Jingzhou 434000, China.
Lian LiuMedical School of Yangtze University, Jingzhou 434000, China.
Zhen Zhen LiuMedical School of Yangtze University, Jingzhou 434000, China.
Gautam SethiDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600.ORCID 0000-0002-8677-8475
Bo Xu RenMedical School of Yangtze University, Jingzhou 434000, China.ORCID 0000-0002-3294-3260
Feng Ru TangRadiation Physiology Laboratory, Singapore Nuclear Research and Safety Initiative, National University of Singapore, 1 CREATE Way #04-01, CREATE Tower, Singapore 138602.ORCID 0000-0003-2462-1787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With rapidly increased construction of nuclear power plants worldwide to reduce energy shortage and subsequent environment contamination, routine use of radiotherapy and radiodiagnosis equipment in the clinical medicine, the research on the health effect of radiation exposure has become a very important area to explore. Traditional Chinese Medicine (TCM) may be an ideal candidate therapy as it usually produces fewer side effects even with long-term administration. In this paper, we reviewed current therapeutic approaches to prevent radiation-induced brain neuropathological and functional changes. Neuroprotective effects of TCM in different brain injury models have been briefly summarized. We then reviewed the neuroprotective and radioprotective effect of TCM in different radiation exposure models and discussed the potential molecular mechanism(s) of the neuroprotective and radioprotective effect of TCM. The conclusions and future research directions were made in the last part of the paper.

Identifiers

PMID30598683
PMCPMC6287144

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.