Evidence map›Paper›PMID 30598634›Full record

ArticleJournal of medical biochemistry2018

High-sensitivity Troponins after a Standardized 2-hour Treadmill Run.

Pavel Broz, Daniel Rajdl, Jaroslav Novak, Milan Hromadka, Jaroslav Racek, Ladislav Trefil, Vaclav Zeman

Abstract read
In one paragraph

Article in Journal of medical biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Assessment of Selected Exercise-induced CD3Journal of medical biochemistry · 2019
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pavel BrozInstitute of Clinical Biochemistry and Haematology, University Hospital in Pilsen, Pilsen, Czech Republic.
Daniel RajdlInstitute of Clinical Biochemistry and Haematology, University Hospital in Pilsen, Pilsen, Czech Republic.
Jaroslav NovakDepartment of Sports Medicine, Charles University in Prague, Prague, Czech Republic.
Milan HromadkaDepartment of Cardiology, University Hospital in Pilsen, Pilsen, Czech Republic.
Jaroslav RacekInstitute of Clinical Biochemistry and Haematology, University Hospital in Pilsen, Pilsen, Czech Republic.
Ladislav TrefilInstitute of Clinical Biochemistry and Haematology, University Hospital in Pilsen, Pilsen, Czech Republic.
Vaclav ZemanDepartment of Sports Medicine, Charles University in Prague, Prague, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to examine high-sensitivity troponin T and I (hsTnT and hsTnI) after a treadmill run under laboratory conditions and to find a possible connection with echocardiographic, laboratory and other assessed parameters.

methodsNineteen trained men underwent a standardized 2-hour-long treadmill run. Concentrations of hsTnT and hsTnI were assessed before the run, 60, 120 and 180 minutes after the start and 24 hours after the run. Changes in troponins were tested using non-parametric analysis of variance (ANOVA). The multiple linear regression model was used to find the explanatory variables for hsTnT and hsTnI changes. Values of troponins were evaluated using the 0h/1h algorithm.

resultsChanges in hsTnT and hsTnI levels were statistically significant (p<0.0001 and p<0.0001, respectively). In a multiple regression model (adjusted R

conclusionsRelative LV wall thickness, creatinine changes, training volume and body temperature after the run can predict changes in hsTnT and hsTnI levels. When medical attention is needed after physical exercise, hsTn levels should be tested only when clinical suspicion and the patient's history indicate a high probability of myocardial damage.

Indexed as

echocardiographyhigh-sensitivity troponinsrunningstandardized exercise

Identifiers

PMID30598634
PMCPMC6298465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.