Evidence map›Paper›PMID 30598579›Full record

ArticleWorld journal of gastroenterology2018

Taíssa Araújo, André Khayat, Luciana Quintana, Danielle Calcagno, Ronald Mourão, Antônio Modesto, Juliana Paiva, Adhara Lima, Fabiano Moreira, Edivaldo Oliveira and 7 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Non-Coding RNA in Penile Cancer.Frontiers in oncology · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. [Single nucleotide polymorphism of rs28416520 inNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
  15. PDE4 subtypes in cancer.Oncogene · 2020
    Review
  16. piRNAs in Gastric Cancer: A New Approach Towards Translational Research.International journal of molecular sciences · 2020
    Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Taíssa AraújoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
André KhayatNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Luciana QuintanaNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Danielle CalcagnoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Ronald MourãoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Antônio ModestoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Juliana PaivaNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Adhara LimaNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Fabiano MoreiraNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Edivaldo OliveiraLaboratório de Cultura de Tecidos e Citogenética, Instituto Evandro Chagas, Belém 66087-082, Brazil.
Michel SouzaLaboratório de Cultura de Tecidos e Citogenética, Instituto Evandro Chagas, Belém 66087-082, Brazil.
Moneeb OthmanInstitute of Human Genetics, Universitätsklinikum Jena, Jena 07747, Germany.
Thomas LiehrInstitute of Human Genetics, Universitätsklinikum Jena, Jena 07747, Germany.
Eliana AbdelhayLaboratório de Célula Tronco, Centro de Transplante de Medula Óssea, Instituto Nacional de Câncer José Alencar Gomes da Silva, Rio de Janeiro 20230-130, Brazil.
Renata GomesLaboratório de Célula Tronco, Centro de Transplante de Medula Óssea, Instituto Nacional de Câncer José Alencar Gomes da Silva, Rio de Janeiro 20230-130, Brazil.
Sidney SantosNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil.
Paulo AssumpçãoNúcleo de Pesquisas em Oncologia, Universidade Federal do Pará, Belém 66073-000, Brazil. assumpcaopp@gmail.com.
Instituto Evandro Chagas · BRInstituto Nacional do Câncer · BRJena University Hospital · DEUniversidade Federal do Pará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo establish a permanent

methodsCRISPR-Cas9 system used was purchased from Dharmacon GE Life Sciences (Lafayette, CO, United States) and permanent knockout was performed according to manufacturer's recommendations. Wound-healing assay was performed to investigate the effect of

results

conclusionTaken together, these data reinforce the idea that PIWIL1 plays a crucial role in the signaling pathway of gastric cancer, regulating several genes involved in migration and invasion processes; therefore, its use as a therapeutic target may generate promising results in the treatment of gastric cancer.

Indexed as

Gene Expression Regulation, NeoplasticArgonaute ProteinsCarcinogenesisCell Line, TumorCell MovementCell ProliferationCRISPR-Cas SystemsGene Expression ProfilingGene Knockout TechniquesHumansNeoplasm InvasivenessSignal TransductionStomach NeoplasmsArgonaute ProteinsPIWIL1 protein, humanCRISPR-Cas9Gastric cancerInvasionMigrationPiwi like RNA-mediated gene silencing 1

Identifiers

PMID30598579
PMCPMC6305533
OpenAlexW2905988632

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.