Evidence map›Paper›PMID 30598481›Full record

ArticleBiology open2019

The 17β-estradiol induced upregulation of the adhesion G-protein coupled receptor (ADGRG7) is modulated by ESRα and SP1 complex.

Amani Hassan, Edward T Bagu, Mathieu Levesque, Shunmoogum A Patten, Samira Benhadjeba, Lydia Edjekouane, Isabelle Villemure, André Tremblay, Florina Moldovan

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Amani HassanCHU Sainte Justine Research Center, Montréal H3T 1C5, Canada.ORCID http://orcid.org/0000-0002-0677-9938
Edward T BaguDepartment of Basic Biomedical Sciences, Sanford Medical School, University of South Dakota, Vermillion, SD 57069, USA.ORCID http://orcid.org/0000-0002-6674-0488
Mathieu LevesqueCHU Sainte Justine Research Center, Montréal H3T 1C5, Canada.ORCID http://orcid.org/0000-0003-0273-510X
Shunmoogum A PattenINRS-Institute Armand-Frappier, Laval H7V 1B7, Canada.
Samira BenhadjebaCHU Sainte Justine Research Center, Montréal H3T 1C5, Canada.
Lydia EdjekouaneCHU Sainte Justine Research Center, Montréal H3T 1C5, Canada.
Isabelle VillemureDepartment of Mechanical Engineering, Ecole Polytechnique de Montréal, Montréal H3T 1J4, Canada.ORCID http://orcid.org/0000-0001-7444-0744
André TremblayCHU Sainte Justine Research Center, Montréal H3T 1C5, Canada.ORCID http://orcid.org/0000-0003-1547-9846
Florina MoldovanCHU Sainte Justine Research Center, Montréal H3T 1C5, Canada florina.moldovan@umontreal.ca.ORCID http://orcid.org/0000-0002-3028-672X
Centre Hospitalier Universitaire Sainte-Justine · CAInstitut National de la Recherche Scientifique · CAPolytechnique Montréal · CAUniversity of South Dakota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physiological role and the regulation of ADGRG7 are not yet elucidated. The functional involvement of this receptor was linked with different physiological process such as reduced body weight, gastrointestinal function and recently, a gene variant in ADGRG7 was observed in patients with adolescent idiopathic scoliosis. Here, we identify the

Indexed as

ADGRG7Adhesion G-protein coupled receptorAISEstradiol (E2)EstrogenGene regulationGPR128Osteoblasts

Identifiers

PMID30598481
PMCPMC6361214
OpenAlexW2908379159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.