ArticleProceedings of the National Academy of Sciences of the United States of America2019
Unregulated antigen-presenting cell activation by T cells breaks self tolerance.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- High-affinity recombinant antibodies enable a sensitive MRGPRX2-specific ELISA for detecting allergic rhinitis and chronic spontaneous urticaria.Analytical and bioanalytical chemistry · 2026Article
- A Novel Approach of T Cell Receptor Classification Reveals Dynamic Interactions Amongst Diet, Microbiota, and Host T Cells.Immune network · 2025Review
- Insights into regulatory T-cell and type-I interferon roles in determining abacavir-induced hypersensitivity or immune tolerance.Frontiers in immunology · 2025Article
- Optimising IL-2 for Cancer Immunotherapy.Immune network · 2024Review
- Excess generation and activation of naturally arising memory-phenotype CD4Frontiers in immunology · 2024Article
- Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level.The Journal of experimental medicine · 2023Article
- Revealing the identity of regulatory T-cell-suppressed self-reactive CD4Cellular & molecular immunology · 2023Article
- Systems immunology of regulatory T cells: can one circuit explain it all?Trends in immunology · 2023Review
- Pre-existing T Cell Memory to Novel Pathogens.ImmunoHorizons · 2023Review
- The endogenous repertoire harbors self-reactive CD4Nature immunology · 2023Article
- Investigation of imbalances in essential/toxic metal levels in the blood of laryngeal cancer patients in comparison with controls.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Article
- The progress of autoimmune hepatitis research and future challenges.Open medicine (Warsaw, Poland) · 2023Review
- Memory-phenotype CD4JMA journal · 2022Review
- Memory-phenotype CD4+ T cells: a naturally arising T lymphocyte population possessing innate immune function.International immunology · 2022Review
- Reciprocal Interactions Between Regulatory T Cells and Intestinal Epithelial Cells.Frontiers in immunology · 2022Review
- Redefining the Foreign Antigen and Self-Driven Memory CD4Frontiers in immunology · 2022Article
- Homeostasis of Naive and Memory T Lymphocytes.Cold Spring Harbor perspectives in biology · 2021Review
- Strength and Numbers: The Role of Affinity and Avidity in the 'Quality' of T Cell Tolerance.Cells · 2021Review
- Innate-adaptive immunity interplay and redox regulation in immune response.Redox biology · 2020Review
- Requirements for the differentiation of innate T-betNature communications · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
T cells proliferate vigorously following acute depletion of CD4
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.