Evidence map›Paper›PMID 30598449›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Allele frequency dynamics in a pedigreed natural population.

Nancy Chen, Ivan Juric, Elissa J Cosgrove, Reed Bowman, John W Fitzpatrick, Stephan J Schoech, Andrew G Clark, Graham Coop

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Pooled it
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  14. Estimating realized relatedness in free-ranging macaques by inferring identity-by-descent segments.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  17. Review
  18. Joining forces to push past paradoxes: Combining quantitative genetics and genomics shows evolution hiding in plain sight.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Microevolutionary change in wild stickleback: Using integrative time-series data to infer responses to selection.Proceedings of the National Academy of Sciences of the United States of America · 2024
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Nancy ChenCenter for Population Biology, University of California, Davis, CA 95616; nancy.chen@rochester.edu.ORCID 0000-0001-8966-3449
Ivan JuricDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195.
Elissa J CosgroveDepartment of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14850.
Reed BowmanAvian Ecology Program, Archbold Biological Station, Venus, FL 33960.ORCID 0000-0002-6027-798X
John W FitzpatrickCornell Lab of Ornithology, Cornell University, Ithaca, NY 14850.
Stephan J SchoechDepartment of Biological Sciences, University of Memphis, Memphis, TN 38152.ORCID 0000-0002-1871-8374
Andrew G ClarkDepartment of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14850.ORCID 0000-0001-7159-8511
Graham CoopCenter for Population Biology, University of California, Davis, CA 95616.
Cornell University · USArchbold Biological Station · USCleveland Clinic · USUniversity of California, Davis · USUniversity of Memphis · USUniversity of Rochester · US

Funding

Genome-wide approaches to polygenic adaptationR01GM108779 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI COOP, GRAHAM · 2014 to 2019
$1.0M
NIGMS NIH HHS R01 GM108779
6 · The paper itself

Abstract

A central goal of population genetics is to understand how genetic drift, natural selection, and gene flow shape allele frequencies through time. However, the actual processes underlying these changes-variation in individual survival, reproductive success, and movement-are often difficult to quantify. Fully understanding these processes requires the population pedigree, the set of relationships among all individuals in the population through time. Here, we use extensive pedigree and genomic information from a long-studied natural population of Florida Scrub-Jays (

Indexed as

Gene FrequencyGenetics, PopulationPedigreeAlgorithmsAnimalsBirdsGenetic VariationModels, GeneticPopulation Dynamicsfitnessgene flowgenetic driftpedigreespopulation genetics

Identifiers

PMID30598449
PMCPMC6369762
OpenAlexW2950463289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.