Evidence map›Paper›PMID 30598446›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

The genomic basis of Red Queen dynamics during rapid reciprocal host-pathogen coevolution.

Andrei Papkou, Thiago Guzella, Wentao Yang, Svenja Koepper, Barbara Pees, Rebecca Schalkowski, Mike-Christoph Barg, Philip C Rosenstiel, Henrique Teotónio, Hinrich Schulenburg

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrei PapkouDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Thiago GuzellaDépartement de Biologie, École Normale Supérieure, 75005 Paris, France.ORCID 0000-0002-1374-7379
Wentao YangDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Svenja KoepperDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Barbara PeesDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Rebecca SchalkowskiDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Mike-Christoph BargDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Philip C RosenstielInstitute for Clinical Molecular Biology, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany.
Henrique TeotónioDépartement de Biologie, École Normale Supérieure, 75005 Paris, France.ORCID 0000-0003-1057-6882
Hinrich SchulenburgDepartment of Evolutionary Ecology and Genetics, Zoological Institute, Christian-Albrechts-Universität Kiel, 24098 Kiel, Germany; hschulenburg@evolbio.mpg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Red Queen dynamics, involving coevolutionary interactions between species, are ubiquitous, shaping the evolution of diverse biological systems. To date, information on the underlying selection dynamics and the involved genome regions is mainly available for bacteria-phage systems or only one of the antagonists of a eukaryotic host-pathogen interaction. We add to our understanding of these important coevolutionary interactions using an experimental host-pathogen model, which includes the nematode

Indexed as

Biological EvolutionModels, BiologicalAnimalsBacillus thuringiensisCaenorhabditisHost-Parasite InteractionsCaenorhabditis eleganscopy number variationhost–pathogen coevolutionpopulation genomicsRed Queen hypothesis

Identifiers

PMID30598446
PMCPMC6338873

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.