ArticleProceedings of the National Academy of Sciences of the United States of America2019
Analysis of research intensity on infectious disease by disease burden reveals which infectious diseases are neglected by researchers.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Age-related spinal degenerative diseases: a quantitative analysis of the dynamic evolution, knowledge structure, and research frontiers in neurological damage.Frontiers in neurology · 2026Pooled it
- Prevalence and associated risk factors of human leishmaniasis in sub-Saharan Africa: an umbrella review.BMC infectious diseases · 2025Pooled it
- National-, institutional-, and individual-level determinants of dental research excellence: an analysis of Stanford-Elsevier lists of the top 2% scholars worldwide (2017-2023).Frontiers in oral health · 2025Pooled it
- Calibration of individual-based models to epidemiological data: A systematic review.PLoS computational biology · 2020Pooled it
- Frequency and distribution of neglected tropical diseases in Mozambique: a systematic review.Infectious diseases of poverty · 2019Pooled it
- Research intensity for neglected tropical diseases and other infectious diseases before and after the COVID-19 pandemic.Journal of global health · 2026Article
- Research capacity and decolonisation in Sub-Saharan Africa: a bibliometric analysis.BMJ global health · 2026Article
- A defined microbiota mouse model forFrontiers in microbiology · 2026Article
- Silver Nanoparticles Functionalized with Polymeric Substances to Reduce the Growth of Planktonic and Biofilm Opportunistic Pathogens.International journal of molecular sciences · 2025Article
- WHO preferred product characteristics for bivalent Salmonella Typhi/Paratyphi A vaccine for comprehensive protection against enteric fever- key considerations and research gaps.Gates open research · 2025Review
- The potential of remote sensing for improved infectious disease ecology research and practice.Proceedings. Biological sciences · 2024Review
- Epidemic Intelligence Threat Reporting Profile in Portugal during the COVID-19: 2 Years of Decrease in Reporting on Non-COVID-19 Threats.Portuguese journal of public health · 2024Article
- Paradigm shift required for translational research on the brain.Experimental & molecular medicine · 2024Review
- Disruption of the C5a/C5aR1 axis confers protection against hookworm infection in lung.Frontiers in immunology · 2024Article
- A QSAR Study for Antileishmanial 2-Phenyl-2,3-dihydrobenzofuransMolecules (Basel, Switzerland) · 2023Article
- HIV research output in African Countries between 1986-2020.PLOS global public health · 2023Article
- Characteristics of retracted research papers before and during the COVID-19 pandemic.Frontiers in medicine · 2023Article
- Paratype: a genotyping tool for Salmonella Paratyphi A reveals its global genomic diversity.Nature communications · 2022Article
- Biosensors for the detection of disease outbreaks through wastewater-based epidemiology.Trends in analytical chemistry : TRAC · 2022Review
- Smartphone-based surface plasmon resonance sensing platform for rapid detection of bacteria.RSC advances · 2022Article
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Abstract
Infectious diseases are associated with considerable morbidity and mortality worldwide. Although human, financial, substantial, and time resources are limited, it is unknown whether such resources are used effectively in research to manage diseases. The correlation between the disability-adjusted life years to represent disease burden and number of publications as a surrogate for research activity was investigated to measure burden-adjusted research intensity for 52 infectious diseases at global and country levels. There was significantly low research intensity for paratyphoid fever and high intensity for influenza, HIV/acquired immunodeficiency syndrome, hepatitis C, and tuberculosis considering their disease burden. We identified the infectious diseases that have received the most attention from researchers and those that have been relatively disregarded. Interestingly, not all so-called neglected tropical diseases were subject to low burden-adjusted research intensity. Analysis of the intensity of infectious disease research at a country level revealed characteristic patterns. These findings provided a basis for further discussion of the more appropriate allocation of resources for research into infectious diseases.
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