Evidence map›Paper›PMID 30598240›Full record

ArticleThe American journal of cardiology2019

Sleep Duration and Mortality in Patients With Coronary Artery Disease.

Jeong Hwan Kim, Salim S Hayek, Yi-An Ko, Chang Liu, Ayman Samman Tahhan, Syed Ali, Ayman Alkhoder, Mohamad Mazen Gafeer, Fahad Choudhary, Ravila Bhimani and 5 more

Abstract read
In one paragraph

Article in The American journal of cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Now is the time to prioritize sleep timing for cardiovascular health.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  3. Article
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  6. Observational
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  11. The association between sleep characteristics and the risk of all-cause mortality among individuals with cardiometabolic multimorbidity: a prospective study of UK Biobank.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Sleep and cardiovascular outcomes in relation to nocturnal hypertension: the J-HOP Nocturnal Blood Pressure Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2021
    Article
  16. Diagnostic and Therapeutic Approach to Sleep Disorders, High Blood Pressure and Cardiovascular Diseases: A Consensus Document by the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jeong Hwan KimEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Salim S HayekEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Yi-An KoEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Chang LiuEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Ayman Samman TahhanEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Syed AliEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Ayman AlkhoderEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Mohamad Mazen GafeerEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Fahad ChoudharyEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Ravila BhimaniEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Shahla DelawallaEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Muaaz ChoudharyEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Dorinda Joy HartsfieldEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia.
Donald L BliwiseDepartment of Neurology, Emory University School of Medicine, Atlanta, Georgia.
Arshed A QuyyumiEmory Clinical Cardiovascular Research Institute, Emory University School of Medicine, Atlanta, Georgia. Electronic address: aquyyum@emory.edu.

Funding

Serious Hazards of Transfusion & Cellular Therapies: Mechanisms and InterventionP01HL086773 · NHLBI · EMORY UNIVERSITY · PI ZIMRING, JAMES C. · 2008 to 2019
$17.9M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Vasiliki Michopoulos · 2018 to 2026
$12.2M
Vascular Responses During Mental StressP01HL101398 · NHLBI · EMORY UNIVERSITY · PI QUYYUMI, ARSHED A · 2010 to 2015
$11.0M
Cell therapy for diabetic peripheral neurovascular complicationsDP3DK094346 · NIDDK · EMORY UNIVERSITY · PI CHENG, XIAODONG, YOON, YOUNG-SUP · 2011 to 2011
$6.1M
The role of the renin-angiotensin-endothelial pathway in ADRF1AG051633 · NIA · EMORY UNIVERSITY · PI HAJJAR, IHAB M, QUYYUMI, ARSHED A · 2015 to 2017
$6.0M
Adverse effects of RBC transfusions: A unifying hypothesisR01HL095479 · NHLBI · EMORY UNIVERSITY · PI ROBACK, JOHN D · 2009 to 2017
$5.2M
Metabolomics of subclinical and clinical cardiovascular diseaseP20HL113451 · NHLBI · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2012 to 2016
$4.3M
Heart Failure Clinical Trials NetworkU10HL110302 · NHLBI · EMORY UNIVERSITY · PI SMITH, ANDREW · 2012 to 2018
$2.5M
Genome-wide association study of MI in CaucasiansR01HL089650 · NHLBI · DECODE GENETICS, INC. · PI GULCHER, JEFFREY R · 2007 to 2010
$2.3M
Emory R38 Research Training ProgramR38AI140299 · NIAID · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, ROUPHAEL, NADINE GEORGES · 2018 to 2021
$1.4M
BIOMARKERS OF ISCHEMIC OUTCOMES IN SYMPTOMATIC INTRACRANIAL STENOSIS (BIOSIS)R01NS064162 · NINDS · EMORY UNIVERSITY · PI FRANKEL, MICHAEL ROSS · 2010 to 2013
$1.0M
Injury and Repair Factors Promoting Atherosclerosis in HIVR56HL126558 · NHLBI · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, QUYYUMI, ARSHED A · 2014 to 2014
$758k
NHLBI NIH HHS P01 HL086773NHLBI NIH HHS P01 HL101398NHLBI NIH HHS P20 HL113451NHLBI NIH HHS R01 HL089650NHLBI NIH HHS R01 HL095479NHLBI NIH HHS R56 HL126558NHLBI NIH HHS U10 HL110302NIAID NIH HHS R38 AI140299NIA NIH HHS RF1 AG051633NIA NIH HHS U54 AG062334NIDDK NIH HHS DP3 DK094346NINDS NIH HHS R01 NS064162
6 · The paper itself

Abstract

Extremes in sleep duration are associated with higher cardiovascular risk in the general population, but their impact in patients with documented coronary artery disease (CAD) remains unknown and potentially of clinical significance. We hypothesized that both short and long sleep duration are associated with higher mortality in CAD. We inquired about sleep durations in 2,846 patients enrolled in the Emory Cardiovascular Biobank (mean age 64 years, 38% female, 23% Black, and 82% with obstructive CAD, defined by positive coronary angiography), who were then followed for all-cause and cardiovascular mortality. Multivariate Cox proportional hazard models were calculated to examine the association of sleep duration and mortality. Sleep durations of <6.5 hours (short), ≥6.5 to <7.5 hours (normal), and ≥7.5 hours (long) were reported by 39%, 26% and 35% of the cohort, respectively. On follow-up (median 2.8 years), mortality rates were 15%, 11%, and 17%, respectively. After adjusting for demographics and risk factors, both short and long sleep duration were associated with higher all-cause mortality (hazard ratio 1.44, 95% confidence interval [1.10 to 1.89], and 1.41 [1.08 to 1.85], respectively). A similar pattern was demonstrated for cardiovascular mortality only for short (hazard ratio 1.48 [1.05 to 2.09]), but not long sleep duration. In conclusion, in patients with frank CAD, both short and long sleep duration were independently associated with higher all-cause mortality, and short sleep was independently associated with higher cardiovascular mortality. In conclusion, our study is the first to extend the observations of sleep duration and mortality from population-based studies to patients with documented cardiac disease.

Indexed as

RegistriesCause of DeathCoronary AngiographyCoronary Artery DiseaseFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRisk AssessmentRisk FactorsSex FactorsSleepTime FactorsUnited States

Identifiers

PMID30598240
PMCPMC6397049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.