Evidence map›Paper›PMID 30597956›Full record

ArticleInternational journal of molecular sciences2018

Ursolic Acid Induces Apoptosis in Colorectal Cancer Cells Partially via Upregulation of MicroRNA-4500 and Inhibition of JAK2/STAT3 Phosphorylation.

Karam Kim, Eun Ah Shin, Ji Hoon Jung, Ji Eon Park, Dong Soub Kim, Bum Sang Shim, Sung-Hoon Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 84 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Karam KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. enpro21@naver.com.
Eun Ah ShinCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. eunah1008@khu.ac.kr.
Ji Hoon JungCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. johnsperfume@khu.ac.kr.
Ji Eon ParkCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. wdnk77@naver.com.
Dong Soub KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. dongsoub@hanmail.net.
Bum Sang ShimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. eshimbs@khu.ac.kr.
Sung-Hoon KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea. sungkim7@khu.ac.kr.ORCID 0000-0003-2423-1973
Kyung Hee University · KR

Funding

National Research Foundation of Korea 2017R1A2A1A17069297
6 · The paper itself

Abstract

Though ursolic acid (UA) isolated from

Indexed as

ApoptosisColorectal NeoplasmsHCT116 CellsHT29 CellsHumansJanus Kinase 2MicroRNAsPhosphorylationPoly(ADP-ribose) PolymerasesSignal TransductionSTAT3 Transcription FactorTriterpenesUp-RegulationUrsolic AcidJAK2 protein, humanJanus Kinase 2microRNA 4500, humanMicroRNAsPoly(ADP-ribose) PolymerasesSTAT3 Transcription FactorTriterpenesUrsolic Acidapoptosiscolorectal cancermiR-4500STAT3ursolic acid

Identifiers

PMID30597956
PMCPMC6337206
OpenAlexW2906767298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.