Evidence map›Paper›PMID 30597923›Full record

ArticleInternational journal of molecular sciences2018

A Novel Approach Based on a Weighted Interactive Network to Predict Associations of MiRNAs and Diseases.

Haochen Zhao, Linai Kuang, Xiang Feng, Quan Zou, Lei Wang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Major-effect quantitative trait locus qLKR4.1 encodes a phospholipase Dδ protein associated with low-KTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Computational Models in Non-Coding RNA and Human Disease.International journal of molecular sciences · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haochen ZhaoKey Laboratory of Hunan Province for Internet of Things and Information Security, Xiangtan University, Xiangtan 411105, China. zhaohc940702@163.com.ORCID 0000-0001-8794-3148
Linai KuangCollege of Computer Engineering & Applied Mathematics, Changsha University, Changsha 410001, China. kuanglinai@xtu.edu.cn.
Xiang FengCollege of Computer Engineering & Applied Mathematics, Changsha University, Changsha 410001, China. fengxiang@xtu.edu.cn.
Quan ZouInstitute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu 610000, China. zouquan@nclab.net.ORCID 0000-0001-6406-1142
Lei WangCollege of Computer Engineering & Applied Mathematics, Changsha University, Changsha 410001, China. wanglei@xtu.edu.cn.ORCID 0000-0002-5065-8447

Funding

CERNET Next Generation Internet Technology Innovation Project NGII20170109National Natural Science Foundation of China 61702180National Natural Science Foundation of China 61873221Natural Science Foundation of Hunan Province 2017JJ5036Natural Science Foundation of Hunan Province 2018JJ4058the CERNET Next Generation Internet Technology Innovation Project NGII20160305
6 · The paper itself

Abstract

Accumulating evidence progressively indicated that microRNAs (miRNAs) play a significant role in the pathogenesis of diseases through many experimental studies; therefore, developing powerful computational models to identify potential human miRNA⁻disease associations is vital for an understanding of the disease etiology and pathogenesis. In this paper, a weighted interactive network was firstly constructed by combining known miRNA⁻disease associations, as well as the integrated similarity between diseases and the integrated similarity between miRNAs. Then, a new computational method implementing the newly weighted interactive network was developed for discovering potential miRNA⁻disease associations (WINMDA) by integrating the

Indexed as

Gene Expression RegulationGene Regulatory NetworksGenetic Predisposition to DiseaseRNA InterferenceAlgorithmsComputational BiologyHumansMicroRNAsReproducibility of ResultsRNA, MessengerROC CurveMicroRNAsRNA, Messengerassociation predictioncomputational prediction modeldiseasesmicroRNApath selection

Identifiers

PMID30597923
PMCPMC6337518

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.