Evidence map›Paper›PMID 30597900›Full record

ArticleGenes2018

Artificial Intelligence and Integrated Genotype⁻Phenotype Identification.

Lewis J Frey

Abstract read
In one paragraph

Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lewis J FreyDepartment of Public Health Sciences, Biomedical Informatics Center, Medical University of South Carolina, Charleston, SC 29425, USA. frey@musc.edu.

Funding

Sociobiological Responses to Stress in Prostate Cancer SurvivorsU54MD010706 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ETHIER, STEPHEN P., HUGHES-HALBERT, CHANITA A. · 2016 to 2020
$8.0M
National Institute on Minority Health and Health Disparities U54-MD010706U.S. Department of Veterans Affairs CIN-13-418
6 · The paper itself

Abstract

The integration of phenotypes and genotypes is at an unprecedented level and offers new opportunities to establish deep phenotypes. There are a number of challenges to overcome, specifically, accelerated growth of data, data silos, incompleteness, inaccuracies, and heterogeneity within and across data sources. This perspective report discusses artificial intelligence (AI) approaches that hold promise in addressing these challenges by automating computable phenotypes and integrating them with genotypes. Collaborations between biomedical and AI researchers will be highlighted in order to describe initial successes with an eye toward the future.

Indexed as

artificial intelligencedata integrationdeep phenotypegenomicsgenotypephenomicsphenotypeprecision medicine informatics

Identifiers

PMID30597900
PMCPMC6356893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.