Evidence map›Paper›PMID 30597581›Full record

SynthesisClinical cardiology2019

CHA2DS2-VASc score predicts atrial fibrillation recurrence after cardioversion: Systematic review and individual patient pooled meta-analysis.

Francesco Vitali, Matteo Serenelli, Juhani Airaksinen, Rita Pavasini, Anna Tomaszuk-Kazberuk, Elzbieta Mlodawska, Samuli Jaakkola, Cristina Balla, Lorenzo Falsetti, Nicola Tarquinio and 4 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. CHABioMed research international · 2020
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Atrial fibrillation in continuous flow-left ventricular assist device (CF-LVAD) patients: impact on pathophysiology.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  6. Article
  7. Review
  8. Predictive ability of serum osmolarity for contrast-induced nephropathy after elective percutaneous coronary intervention: Are we having a new target?The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  9. Article
  10. Usability of CHAFrontiers in cardiovascular medicine · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Predictive value of CHAThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Francesco VitaliCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
Matteo SerenelliCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
Juhani AiraksinenHeart Centre, Turku University Hospital and University of Turku, Turku, Finland.ORCID https://orcid.org/0000-0002-0193-568X
Rita PavasiniCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0002-1763-9711
Anna Tomaszuk-KazberukDepartment of Cardiology, University Hospital in Bialystok, Bialystok, Poland.
Elzbieta MlodawskaDepartment of Cardiology, University Hospital in Bialystok, Bialystok, Poland.
Samuli JaakkolaHeart Centre, Turku University Hospital and University of Turku, Turku, Finland.
Cristina BallaCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
Lorenzo FalsettiInternal and Sub-intensive Medicine Department, A.O.U. "Ospedali Riuniti", Ancona, Italy.
Nicola TarquinioDepartment of Internal Medicine, Ospedale 'S.S. Benvenuti e Rocco', Ancona, Italy.
Roberto FerrariCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
Angelo SqueriMaria Cecilia Hospital, GVM Care and Research, Cotignola, Italy.
Gianluca CampoCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.
Matteo BertiniCardiovascular Center, Azienda Ospedaliero-Universitaria di Ferrara, Ferrara, Italy.ORCID https://orcid.org/0000-0002-5285-7140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite progresses in the treatment of the thromboembolic risk related to atrial fibrillation (AF), the management of recurrences remains a challenge. HYPOTHESIS: To assess if congestive heart failure or left ventricular systolic dysfunction (CHA

methodsSystematic review and individual patient pooled meta-analysis following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. INCLUSION CRITERIA: observational trials in patients with AF undergoing cardioversion, available data on recurrence of AF and available data on CHA

resultsOverall, we collect data of 2889 patients: 61% were male, 50% with hypertension, 12% with diabetes, and 23% with history of ischemic heart disease. The median CHA2DS2-VASc score was 2.. At the multivariate analysis, chronic kidney disease (odds ratio [OR] 1.94; 95% confidence interval [CI] 1.12-3.27; P = 0.01), peripheral artery disease (OR 1.65; 95% CI 1.23-2.19; P < 0,0001), previous use of beta blockers (OR 1.5; 95% CI 1.19-1.88; P < 0.0001), and CHA2DS2-VASc score > 2 (OR 1.37; 95% CI 1.1-1.68; P = 0.002) were independent predictors of early recurrence of AF.

conclusionsCHA2DS2-VASc score predicts early recurrence of AF in the first 30 days after electrical or pharmacological cardioversion. Protocol registration PROSPERO (CRD42017075107).

Indexed as

Atrial FibrillationElectric CountershockGlobal HealthHumansMorbidityRecurrenceRisk AssessmentRisk FactorsSurvival Ratearrhythmiaatrial fibrillationcardioversionCHA2DS2-VAScrecurrence

Identifiers

PMID30597581
PMCPMC6712331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.