Evidence map›Paper›PMID 30597507›Full record

ArticleThrombosis and haemostasis2019

Agonist-Evoked Increases in Intra-Platelet Zinc Couple to Functional Responses.

Niaz S Ahmed, Maria E Lopes Pires, Kirk A Taylor, Nicholas Pugh

Open access · hybridAbstract read
In one paragraph

Article in Thrombosis and haemostasis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. CLIC1 Supports Mechanisms Related to Platelet Activation and Thrombosis.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2025
    Article
  2. Human platelets contain a pool of free zinc in dense granules.Research and practice in thrombosis and haemostasis · 2024
    Article
  3. Delineating Zinc Influx Mechanisms during Platelet Activation.International journal of molecular sciences · 2023
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Niaz S AhmedSchool of Life Sciences, Anglia Ruskin University, Cambridge, United Kingdom.
Maria E Lopes PiresSchool of Life Sciences, Anglia Ruskin University, Cambridge, United Kingdom.
Kirk A TaylorCardio-Respiratory Interface Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Nicholas PughSchool of Life Sciences, Anglia Ruskin University, Cambridge, United Kingdom.
Anglia Ruskin University · GBImperial College London · GB

Funding

British Heart Foundation PG/14/47/30912
6 · The paper itself

Abstract

backgroundZinc (Zn

objectivesThis article determines whether cytosolic Zn

methodsChanges in [Zn

resultsIncreases of intra-platelet Fluozin-3 (Fz-3) fluorescence occurred in response to stimulation by cross-linked collagen-related peptide (CRP-XL) or U46619, consistent with a rise of [Zn

conclusionThese data suggest that agonist-evoked fluctuations in intra-platelet Zn

Indexed as

Blood PlateletsCalciumCationsChelating AgentsCross-Linking ReagentsCytosolHumansIonophoresMicroscopy, ConfocalOxidation-ReductionPhosphatidylserinesPhosphorylationPlatelet ActivationPlatelet AggregationPlatelet Glycoprotein GPIIb-IIIa ComplexPolycyclic CompoundsCalciumCationsChelating AgentsCross-Linking ReagentsFluoZin-3IonophoresPhosphatidylserinesPlatelet Glycoprotein GPIIb-IIIa ComplexPolycyclic CompoundsZinc

Identifiers

PMID30597507
PMCPMC6327715
OpenAlexW2908501232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.