Evidence map›Paper›PMID 30597416›Full record

ArticleAlcohol (Fayetteville, N.Y.)2019

Influence of low-dose alcohol consumption on post-ischemic inflammation: Role of cystathionine γ-lyase.

Kimberly D McCarter, Chun Li, Jiyu Li, Guodong Xu, Hong Sun

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alcohol (Fayetteville, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Kimberly D McCarterDepartment of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States.
Chun LiDepartment of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States.
Jiyu LiDepartment of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States.
Guodong XuDepartment of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States; Department of Neurology, Hebei General Hospital, Shijiazhuang, Hebei 050051, China.
Hong SunDepartment of Cellular Biology & Anatomy, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA, United States. Electronic address: hsun1@lsuhsc.edu.
Louisiana State University Health Sciences Center Shreveport · US

Funding

Light Alcohol Consumption and Ischemic StrokeR01AA023610 · NIAAA · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Hong Sun · 2016 to 2026
$3.1M
NIAAA NIH HHS R01 AA023610
6 · The paper itself

Abstract

Low-dose alcohol consumption (LAC) has been shown to suppress post-ischemic inflammation and alleviate cerebral ischemia/reperfusion (I/R) injury. Cystathionine γ-Lyase (CSE) is one of the enzymes that endogenously produce hydrogen sulfide (H

Indexed as

AlanineAlkynesAnimalsBiomarkersCerebral CortexCystathionine gamma-LyaseEthanolGlycineHydrogen SulfideInfarction, Middle Cerebral ArteryInflammationMaleMiceProtective AgentsReperfusion Injury3-cyanoalanineAlanineAlkynesBiomarkersCystathionine gamma-LyaseEthanolGlycineHydrogen SulfidepropargylglycineProtective AgentsBrainCystathionine γ-lyaseEthanolInflammationIschemia/reperfusion

Identifiers

PMID30597416
PMCPMC6416088
OpenAlexW2888158586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.