Evidence map›Paper›PMID 30597156›Full record

ArticleMathematical biosciences2019

A forecasting model of disease prevalence based on the McKendrick-von Foerster equation.

I Akushevich, A Yashkin, J Kravchenko, F Fang, K Arbeev, F Sloan, A I Yashin

Abstract read
In one paragraph

Article in Mathematical biosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

I AkushevichBiodemography of Aging Research Unit, Center for Population Health and Aging, Duke University, Durham, NC, United States. Electronic address: igor.akushevich@duke.edu.
A YashkinBiodemography of Aging Research Unit, Center for Population Health and Aging, Duke University, Durham, NC, United States.
J KravchenkoDepartment of Surgery, Duke University School of Medicine, Durham, NC, United States.
F FangCenter for Genomics in Public Health and Medicine, RTI International, Research Triangle Park, NC, United States.
K ArbeevBiodemography of Aging Research Unit, Center for Population Health and Aging, Duke University, Durham, NC, United States.
F SloanDepartment of Economics, Duke University, Durham, NC, United States.
A I YashinBiodemography of Aging Research Unit, Center for Population Health and Aging, Duke University, Durham, NC, United States.

Funding

STALLARD Admin Supp: Predicting Future Care Needs and Costs for Individual Medicare Enrollees with Incident Suspected Alzheimer's DiseaseP30AG034424 · NIA · DUKE UNIVERSITY · PI SCOTT M. LYNCH · 2009 to 2026
$12.2M
Relationships among Genetic Regulators of Aging Health and LifespanP01AG043352 · NIA · DUKE UNIVERSITY · PI YASHIN, ANATOLIY I · 2014 to 2018
$8.7M
Genetics of changes in population pyramids: Implications for health forecasting with a focus on Alzheimer's Disease and related dementiasRF1AG046860 · NIA · DUKE UNIVERSITY · PI YASHIN, ANATOLIY I · 2019 to 2019
$3.1M
YASHIN Admin Supp: Time Trends in Alzheimer's Disease: Addressing the Changing Role of Risk Factors and Instrument ValidityR01AG046860 · NIA · DUKE UNIVERSITY · PI YASHIN, ANATOLIY I · 2014 to 2018
$3.1M
VISUAL IMPAIRMENT, TREATMENT, AND EFFECTS ON THE ELDERLYR01AG017473 · NIA · DUKE UNIVERSITY · PI SLOAN, FRANK A · 2001 to 2012
$1.7M
Explanations of Racial Disparities in Active LifeR03HD050374 · NICHD · PRINCETON UNIVERSITY · PI LYNCH, SCOTT M · 2005 to 2006
$156k
NIA NIH HHS P01 AG043352NIA NIH HHS P30 AG034424NIA NIH HHS R01 AG017473NIA NIH HHS R01 AG046860NIA NIH HHS RF1 AG046860NICHD NIH HHS R03 HD050374
6 · The paper itself

Abstract

A new model for disease prevalence based on the analytical solutions of McKendric-von Foerster's partial differential equations is developed. Derivation of the model and methods to cross check obtained results are explicitly demonstrated. Obtained equations describe the time evolution of the healthy and unhealthy age-structured sub-populations and age patterns of disease prevalence. The projection of disease prevalence into the future requires estimates of time trends of age-specific disease incidence, relative survival functions, and prevalence at the initial age and year available in the data. The computational scheme for parameter estimations using Medicare data, analytical properties of the model, application for diabetes prevalence, and relationship with partitioning models are described and discussed. The model allows natural generalization for the case of several diseases as well as for modeling time trends in cause-specific mortality rates.

Indexed as

ForecastingModels, TheoreticalPrevalenceDiabetes Mellitus, Type 2HumansMedicareUnited StatesForecastingLee-CarterMedicarePartitioningPrevalenceProjectionsTime seriesType II Diabetes

Identifiers

PMID30597156
PMCPMC6916255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.