ArticleInternational journal of epidemiology2019
The contribution of drug-related deaths to the US disadvantage in mortality.
Article in International journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Insights into US life expectancy stagnation from birth cohort mortality dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Life Expectancy and Health Expectancy in the Twenty-first Century: The Unthinkable, the Inconceivable, and the Unknowable.Demography · 2025Article
- Excess Mortality Estimation.Annual review of statistics and its application · 2025Article
- State drug caps associated with fewer Medicaid-covered prescriptions for opioid use disorder, 2017-2022.Health affairs scholar · 2024Article
- Article
- Rising childhood income inequality and declining Americans' health.Social science & medicine (1982) · 2022Article
- Socioeconomic Disparities Do Not Explain the U.S. International Disadvantage in Mortality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Smoothing, Decomposing and Forecasting Mortality Rates.European journal of population = Revue europeenne de demographie · 2021Article
- Diversification in causes of death in low-mortality countries: emerging patterns and implications.BMJ global health · 2020Article
- Article
- Influences on advance practice nursing education to prescribe medications for opioid use disorder.Nursing outlookArticle
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
Abstract
backgroundThe USA ranks last in life expectancy among high-income countries. Since 2000, excess US mortality has been particularly concentrated in the working ages, which are also the ages hardest hit by the increase in drug deaths. This study measures the effect of drug-related mortality on the gap in life expectancy between the USA and other countries.
methodsData from the Human Mortality Database and the World Health Organization were combined to construct age-standardized mortality rates for 2000-14 in 12 high-income countries and the USA for seven broad causes of death, including drug use. The contribution of each cause to the difference in life expectancy between the USA and the other 12 countries was estimated.
resultsIn 2014, the increase in drug-related deaths accounted for 10-15% of the US disadvantage in mortality, but with marked differences by age group. For working-age men, the increase in drug-related deaths accounted for up to 38% of the difference. Overall, American mortality is higher than the comparison countries across a wide range of causes.
conclusionsThe severity of the drug epidemic appears to be specific to the USA, but it only partly contributes to the American shortfall in mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.