Evidence map›Paper›PMID 30596755›Full record

ArticlePloS one2018

Yeast screening and cell immobilization on inert supports for ethanol production from cheese whey permeate with high lactose loads.

Rebeca Díez-Antolínez, María Hijosa-Valsero, Ana I Paniagua-García, Jerson Garita-Cambronero, Xiomar Gómez

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Physiological characterization ofFrontiers in microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebeca Díez-AntolínezCenter of Biofuels and Bioproducts, Instituto Tecnológico Agrario de Castilla y León (ITACyL), Villarejo de Órbigo, León, Spain.ORCID 0000-0001-7604-1886
María Hijosa-ValseroCenter of Biofuels and Bioproducts, Instituto Tecnológico Agrario de Castilla y León (ITACyL), Villarejo de Órbigo, León, Spain.
Ana I Paniagua-GarcíaCenter of Biofuels and Bioproducts, Instituto Tecnológico Agrario de Castilla y León (ITACyL), Villarejo de Órbigo, León, Spain.
Jerson Garita-CambroneroCenter of Biofuels and Bioproducts, Instituto Tecnológico Agrario de Castilla y León (ITACyL), Villarejo de Órbigo, León, Spain.
Xiomar GómezChemical and Environmental Bioprocess Engineering Group, Natural Resources Institute (IRENA), University of León, León, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eight yeast strains of the genera Saccharomyces and Kluyveromyces were screened to ferment high lactose-load cheese whey permeate (CWP) (>130 g/L lactose) without nutrient supplementation. The fermentation conditions (temperature, pH and time) were optimized to maximize the fermentation performance (ethanol titer, ethanol yield and lactose consumption) for the two preselected strains, K. marxianus DSM 5422 and S. cerevisiae Ethanol Red, using a response surface methodology (RSM). Under optimized conditions, K. marxianus DSM 5422 attained ethanol titers of 6% (v/v) in only 44 h. Moreover, the feasibility of immobilizing this strain on four different inorganic supports (plastic, glass and Tygon silicone Raschig rings and alumina beads) was assessed. Glass Raschig rings and alumina beads showed a more stable performance over time, yielding ethanol titers of 60 g/L during 1,000 hours, which remarkably reduces yeast cultivation costs. Results demonstrate the feasibility of using CWP for successful ethanol production in a simple and economical process, which represents an attractive alternative for waste treatment in dairy industries.

Indexed as

CheeseCells, ImmobilizedEthanolKluyveromycesSaccharomyces cerevisiaeWheyEthanol

Identifiers

PMID30596755
PMCPMC6312371

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.