Evidence map›Paper›PMID 30596736›Full record

ArticlePloS one2018

High-resolution magic angle spinning NMR studies for metabolic characterization of Arabidopsis thaliana mutants with enhanced growth characteristics.

Dieuwertje Augustijn, Niels van Tol, Bert J van der Zaal, Huub J M de Groot, A Alia

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. HR-MAS NMR Applications in Plant Metabolomics.Molecules (Basel, Switzerland) · 2021
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dieuwertje AugustijnLeiden Institute of Chemistry, Leiden University, RA Leiden, The Netherlands.
Niels van TolInstitute of Biology Leiden, Leiden University, BE, Leiden, The Netherlands.
Bert J van der ZaalInstitute of Biology Leiden, Leiden University, BE, Leiden, The Netherlands.
Huub J M de GrootLeiden Institute of Chemistry, Leiden University, RA Leiden, The Netherlands.
A AliaLeiden Institute of Chemistry, Leiden University, RA Leiden, The Netherlands.ORCID 0000-0002-4900-9749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing smart crops which yield more biomass to meet the increasing demand for plant biomass has been an active area of research in last few decades. We investigated metabolic alterations in two Arabidopsis thaliana mutants with enhanced growth characteristics that were previously obtained from a collection of plant lines expressing artificial transcription factors. The metabolic profiles were obtained directly from intact Arabidopsis leaves using high-resolution magic angle spinning (HR-MAS) NMR. Multivariate analysis showed significant alteration of metabolite levels between the mutants and the wild-type Col-0. Interestingly, most of the metabolites that were reduced in the faster-growing mutants are generally involved in the defence against stress. These results suggest a growth-defence trade-off in the phenotypically engineered mutants. Our results further corroborate the idea that plant growth can be enhanced by suppressing defence pathways.

Indexed as

Magnetic Resonance SpectroscopyMetabolomicsPlant DevelopmentArabidopsisMetabolomeModels, BiologicalPhenotype

Identifiers

PMID30596736
PMCPMC6312362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.