ArticlePloS one2018
Impacts of impaired face perception on social interactions and quality of life in age-related macular degeneration: A qualitative study and new community resources.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 65 citations in OpenAlex.
- A Randomized Study of Nutritional Supplementation in Patients with Unilateral Wet Age-Related Macular Degeneration.Nutrients · 2021Trial
- Unveiling Face Recognition Challenges and Awareness in Autism Spectrum Disorder: Insights from the Italian Famous Face Test (IT-FFT).Journal of autism and developmental disorders · 2026Article
- Central Vision Loss Alters Internal Emotion Representations: Evidence from a Generative Genetic Algorithm Paradigm.bioRxiv : the preprint server for biology · 2026Article
- A Visual Telerehabilitation Program in Virtual Reality for Age-Related Macular Degeneration: Randomized Feasibility and Proof-of-Concept Trial.JMIR rehabilitation and assistive technologies · 2026Article
- Psychometric Assessment of the Metamorphopsia Questionnaire in Patients with Macular Diseases Receiving Anti-Vascular Endothelial Growth Factor Treatment.Journal of clinical medicine · 2026Article
- Patient-Reported Quality of Life and Treatment Experiences Among Patients with Neovascular Age-Related Macular Degeneration Receiving Intravitreal Aflibercept in Colombia: A Qualitative Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Neurobehavioral Changes in Macular Degeneration: Spatial Frequency Use in Scene Recognition.Investigative ophthalmology & visual science · 2025Article
- Undetected Visual Impairment Among Older People and Its Impact on Vision-Related Quality of Life: A Study Protocol.Nursing reports (Pavia, Italy) · 2025Article
- Determinants of Healthcare Professionals' Knowledge on Age-Related Macular Degeneration Risk Factors in Ethiopia.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Prioritising the Burden of Geographic Atrophy and Treatment Expectations: A Modified Nominal Group Technique Study with International Patient-Led Organisations.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Aligning Visual Prosthetic Development With Implantee Needs.Translational vision science & technology · 2024Article
- Aligning visual prosthetic development with implantee needs.medRxiv : the preprint server for health sciences · 2024Article
- Prosopagnosia: face blindness and its association with neurological disorders.Brain communications · 2024Article
- Drift-diffusion modeling reveals that masked faces are preconceived as unfriendly.Scientific reports · 2023Article
- Empowerment-Based Physical Activity Intervention for People with Advanced Dry Age-Related Macular Degeneration: Mixed-Methods Protocol.International journal of environmental research and public health · 2022Article
- Optic Flow Processing in Patients With Macular Degeneration.Investigative ophthalmology & visual science · 2022Article
- Identifying the content for an item bank and computerized adaptive testing system to measure the impact of age-related macular degeneration on health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Face masks disrupt holistic processing and face perception in school-age children.Cognitive research: principles and implications · 2022Article
- Enhancing socio-emotional communication and quality of life in young cochlear implant recipients: Perspectives from parameter-specific morphing and caricaturing.Frontiers in neuroscience · 2022Article
- Relationships between retinal structure and function and vision-related quality of life measures in advanced age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsPrevious studies and community information about everyday difficulties in age-related macular degeneration (AMD) have focussed on domains such as reading and driving. Here, we provide the first in-depth examination of how impaired face perception impacts social interactions and quality of life in AMD. We also develop a Faces and Social Life in AMD brochure and information sheet, plus accompanying conversation starter, aimed at AMD patients and those who interact with them (family, friends, nursing home staff).
methodSemi-structured face-to-face interviews were conducted with 21 AMD patients covering the full range from mild vision loss to legally blind. Thematic analysis was used to explore the range of patient experiences.
resultsPatients reported faces appeared blurred and/or distorted. They described recurrent failures to recognise others' identity, facial expressions and emotional states, plus failures of alternative non-face strategies (e.g., hairstyle, voice). They reported failures to follow social nuances (e.g., to pick up that someone was joking), and feelings of missing out ('I can't join in'). Concern about offending others (e.g., by unintentionally ignoring them) was common, as were concerns of appearing fraudulent ('Other people don't understand'). Many reported social disengagement. Many reported specifically face-perception-related reductions in social life, confidence, and quality of life. All effects were observed even with only mild vision loss. Patients endorsed the value of our Faces and Social Life in AMD Information Sheet, developed from the interview results, and supported future technological assistance (digital image enhancement).
conclusionPoor face perception in AMD is an important domain contributing to impaired social interactions and quality of life. This domain should be directly assessed in quantitative quality of life measures, and in resources designed to improve community understanding. The identity-related social difficulties mirror those in prosopagnosia, of cortical rather than retinal origin, implying findings may generalise to all low-vision disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.