Evidence map›Paper›PMID 30596572›Full record

ArticleIEEE transactions on medical imaging2019

Design and Demonstration of a Configurable Imaging Platform for Combined Laser, Ultrasound, and Elasticity Imaging.

Heechul Yoon, Yiying I Zhu, Steven K Yarmoska, Stanislav Y Emelianov

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Tri-modalityPhotoacoustics · 2024
    Article
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  12. Leveraging the Imaging Transmit Pulse to Manipulate Phase-Change Nanodroplets for Contrast-Enhanced Ultrasound.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Heechul Yoon
Yiying I Zhu
Steven K Yarmoska
Stanislav Y Emelianov
Georgia Institute of Technology · US

Funding

Optical elastography for assessment of myocardial regenerationR01HL130804 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI LARIN, KIRILL V, MARTIN, JAMES F · 2016 to 2019
$2.9M
Functional, cellular, and molecular imaging and therapy monitoring using ultrasouR01CA158598 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y, ESTEVA, FRANCISCO J · 2012 to 2018
$2.8M
Magnetic Steering and Longitudinal Visualization of Stem Cells for Trabecular Meshwork Therapy in GlaucomaR01EY030071 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y, ETHIER, C ROSS · 2019 to 2022
$2.3M
Molecular photothermal therapy of cancer using targeted metal nanoparticlesR01CA149740 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y · 2010 to 2014
$1.6M
Ultrasound-guided photoacoustic imaging and tracking of stem cells in the spinal cordR21NS112885 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y · 2020 to 2020
$434k
Ultrasound-Guided Molecular Photoacoustic Imaging of BrainR21NS102860 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y · 2017 to 2018
$413k
Perfluorocarbon Nanodroplets for the Detection and Treatment of Nodal MetastasesF30CA216939 · NCI · EMORY UNIVERSITY · PI YARMOSKA, STEVEN KARL · 2017 to 2021
$250k
NCI NIH HHS F30 CA216939NCI NIH HHS R01 CA149740NCI NIH HHS R01 CA158598NEI NIH HHS R01 EY030071NHLBI NIH HHS R01 HL130804NINDS NIH HHS R21 NS102860NINDS NIH HHS R21 NS112885
6 · The paper itself

Abstract

This paper introduces a configurable combined laser, ultrasound, and elasticity (CLUE) imaging platform. The CLUE platform enables imaging sequences capable of simultaneously providing quantitative acoustic, optical, and mechanical contrast for comprehensive diagnosis and monitoring of complex diseases, such as cancer. The CLUE imaging platform was developed on a Verasonics ultrasound scanner integrated with a pulsed laser, and it was designed to be modular and scalable to allow researchers to create their own specific imaging sequences efficiently. The CLUE imaging platform and sequence were demonstrated in a tissue-mimicking phantom containing a stiff inclusion labeled with optically-activated nanodroplets and in an ex vivo mouse spleen. We have shown that CLUE imaging can simultaneously capture multi-functional imaging signals providing quantitative information on tissue.

Indexed as

AnimalsImage Processing, Computer-AssistedLasersMicePhantoms, ImagingSoftwareSpleenTransducersUltrasonography

Identifiers

PMID30596572
PMCPMC7286075
OpenAlexW2907345387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.