ArticleJournal of the American Heart Association2019
Improving Care of STEMI in the United States 2008 to 2012.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Reperfusion Strategy of ST-Elevation Myocardial Infarction: A Meta-Analysis of Primary Percutaneous Coronary Intervention and Pharmaco-Invasive Therapy.Frontiers in cardiovascular medicine · 2022Pooled it
- Definition of left ventricular remodelling following ST-elevation myocardial infarction: a systematic review of cardiac magnetic resonance studies in the past decade.Heart failure reviews · 2022Pooled it
- Development, validation and visualization of a nomogram for the prediction of in-hospital cardiac arrest in patients after successful primary PCI for STEMI.BMC cardiovascular disorders · 2026Article
- Trends in mortality due to acute myocardial infarction and pneumonia among older adults in the U.S.: a CDC wonder analysis (1999-2023).Frontiers in cardiovascular medicine · 2026Article
- Development and Validation of a Machine Learning Model to Predict the Risk of Medical Decision-Making Delay in Acute Myocardial Infarction Patients From Multicenter Tertiary Hospitals in China.International journal of general medicine · 2026Article
- Disparities by Race and Ethnicity in Percutaneous Coronary Intervention.JAMA network open · 2025Article
- Acute Myocardial Infarction Mortality in the Older Population of the United States: An Analysis of Demographic and Regional Trends and Disparities from 1999 to 2022.Journal of clinical medicine · 2025Article
- Narrative review: updates and strategies for reducing door-to-balloon time in ST-elevation myocardial infarction care.Frontiers in cardiovascular medicine · 2025Review
- The Challenge of Improving Outcomes After a Myocardial Infarction in Sub-Saharan Africa.JACC. Advances · 2024Article
- A Guide to Implementation Science for Phase 3 Clinical Trialists: Designing Trials for Evidence Uptake.Journal of the American College of Cardiology · 2024Review
- Microvascular Obstruction in Patients With Anterior STEMI Treated With Supersaturated Oxygen.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Factors Influencing Time to First Medical Contact in Patients with Acute ST-Segment Elevation Myocardial Infarction: A Retrospective Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Article
- Advancements in reperfusion rates and quality of care for ST-segment elevation myocardial infarction: a ten-year evaluation of Salvador's STEMI network.Frontiers in cardiovascular medicine · 2024Article
- Ten-year review of ST-Segment Elevation Myocardial Infarction (STEMI) in Tanzania: a single center retrospective review.The Pan African medical journal · 2024Article
- Patient and Hospital Characteristics Associated With the Interhospital Transfer of Adult Patients With Sepsis.Critical care explorations · 2023Article
- Unpacking Regionalization of Sepsis Care Using Hospital Capability Assessments.Critical care medicine · 2023Article
- The Relationship Between Hospital Capability and Mortality in Sepsis: Development of a Sepsis-Related Hospital Capability Index.Critical care medicine · 2023Article
- Interfacility Transfer of Uninsured vs Insured Patients With ST-Segment Elevation Myocardial Infarction in California.JAMA network open · 2023Observational
- Interhospital Transfer versus Direct Admission in Patients with Acute ST-Segment Elevation Myocardial Infarction.The International journal of angiology : official publication of the International College of Angiology, Inc · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background We aimed to determine the change in treatment strategies and times to treatment over the first 5 years of the Mission: Lifeline program. Methods and Results We assessed pre- and in-hospital care and outcomes from 2008 to 2012 for patients with ST -segment-elevation myocardial infarction at US hospitals, using data from the National Cardiovascular Data Registry Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines Registry. In-hospital adjusted mortality was calculated including and excluding cardiac arrest as a reason for primary percutaneous coronary intervention delay. A total of 147 466 patients from 485 hospitals were analyzed. There was a decrease in the proportion of eligible patients not treated with reperfusion (6.2% versus 3.3%) and treated with fibrinolytic therapy (13.4% versus 7.0%). Median time from symptom onset to first medical contact was unchanged (≈50 minutes). Use of prehospital ECGs increased (45% versus 71%). All major reperfusion times improved: median first medical contact-to-device for emergency medical systems transport to percutaneous coronary intervention-capable hospitals (93 to 84 minutes), first door-to-device for transfers for primary percutaneous coronary intervention (130 to 112 minutes), and door-in-door-out at non-percutaneous coronary intervention-capable hospitals (76 to 62 minutes) (all P<0.001 over 5 years). Rates of cardiogenic shock and cardiac arrest, and overall in-hospital mortality increased (5.7% to 6.3%). Adjusted mortality excluding patients with known cardiac arrest decreased by 14% at 3 years and 25% at 5 years ( P<0.001). Conclusions Quality of care for patients with ST -segment-elevation myocardial infarction improved over time in Mission: Lifeline, including increased use of reperfusion therapy and faster times-to-treatment. In-hospital mortality improved for patients without cardiac arrest but did not appear to improve overall as the number of these high-risk patients increased.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.