Evidence map›Paper›PMID 30596193›Full record

ArticleAfrican journal of infectious diseases2019

USAGE OF A RAPID DIAGNOSTIC TEST FOR MALARIA IN CHILDREN.

Céline Nguefeu Nkenfou, Vestale Ngo Hell, Nguefack-Tsague Georges, Marie Nicole Ngoufack, Carine Nguefeu Nkenfou, Nelly Kamgaing, Alexis Ndjolo

Open access · greenAbstract read
In one paragraph

Article in African journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Céline Nguefeu NkenfouLaboratory of Systems Biology, "Chantal Biya" International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon.
Vestale Ngo HellCatholic University, School of Health Sciences, Yaounde, Cameroon.
Nguefack-Tsague GeorgesFaculty of Medicine and Biomedical Sciences, University of Yaounde, Yaounde, Cameroon.
Marie Nicole NgoufackLaboratory of Systems Biology, "Chantal Biya" International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon.
Carine Nguefeu NkenfouFaculty of Sciences, University of Yaounde I, Yaounde, Cameroon.
Nelly KamgaingLaboratory of Systems Biology, "Chantal Biya" International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon.
Alexis NdjoloLaboratory of Systems Biology, "Chantal Biya" International Reference Centre for Research on HIV/AIDS Prevention and Management (CBIRC), Yaounde, Cameroon.
Université de Yaoundé I · CMCentre International De Reference Chantal Biya · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria is still the primary cause of pediatric deaths. The efficient management of pediatric malaria requires its rapid and accurate diagnosis. To fulfill this requirement, rapid diagnostic tests have been developed, but their evaluation before commercialization is never exhaustive. The aim of this study was to evaluate the performance of a rapid diagnostic test (SD Bioline Malaria Antigen P.f/Pan) to diagnose malaria in children. MATERIALS AND

methodsTesting was conducted on children aged between 6 months and 15 years who were examined at the "Centre Mère Enfant (CME) of the "Chantal Biya" Foundation (FCB). as a result of fever. Enrollment took place from April to October 2014. All children presenting with fever were sampled (3ml of blood). These blood samples were tested for malaria using microscopy on a thick blood smear and by a rapid diagnostic test (RDT) SD Bioline

resultsA total of 249 children were enrolled in this study. Malaria presence as determined by microscopy and by RDT was 30.9% and 58.2% respectively. The sensitivity, specificity, positive and negative predictive values compared to microscopy were: 75; 48.8; 39, and 81.6%. With these performances, the malaria SD Bioline rapid test presents lower values compared to WHO recommendations for rapid tests (sensitivity > 95%) in children.

conclusionSD Bioline Malaria Antigen P.f/Pan test should only be used in peripheral health structures that lack resources, and should be aided by clinical diagnosis.

Indexed as

Keyword: MalariaMicroscopyPerformanceRapid diagnostic testthick blood smear

Identifiers

PMID30596193
PMCPMC6305079
OpenAlexW2905383136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.