Evidence map›Paper›PMID 30596133›Full record

ArticleData in brief2019

Spatial distribution of marker gene activity in the mouse lung during alveolarization.

M Cecilia Ljungberg, Mayce Sadi, Yunguan Wang, Bruce J Aronow, Yan Xu, Rong J Kao, Ying Liu, Nathan Gaddis, Maryanne E Ardini-Poleske, Tipparat Umrod and 8 more

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Cell Population-resolved Multiomics Atlas of the Developing Lung.American journal of respiratory cell and molecular biology · 2025
    Article
  3. Review
  4. LungMAP Portal Ecosystem: Systems-level Exploration of the Lung.American journal of respiratory cell and molecular biology · 2024
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 1 country.

M Cecilia LjungbergBaylor College of Medicine, Houston, TX, USA.
Mayce SadiTexas Advanced Computing Center, The University of Texas at Austin, Austin, TX, USA.
Yunguan WangHarvard Medical School, Boston, MA, USA.
Bruce J AronowCincinnati Children׳s Hospital Medical Center, Cincinnati, OH, USA.
Yan XuCincinnati Children׳s Hospital Medical Center, Cincinnati, OH, USA.
Rong J KaoBaylor College of Medicine, Houston, TX, USA.
Ying LiuBaylor College of Medicine, Houston, TX, USA.
Nathan GaddisRTI International, Research Triangle Park, NC, USA.
Maryanne E Ardini-PoleskeRTI International, Research Triangle Park, NC, USA.
Tipparat UmrodTexas Advanced Computing Center, The University of Texas at Austin, Austin, TX, USA.
Namasivayam AmbalavananUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Teodora NicolaUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Naftali KaminskiYale University, New Haven, CN.
Farida AhangariYale University, New Haven, CN.
Ryan SontagPacific Northwest National Laboratory, Richland, WA, USA.
Richard A CorleyPacific Northwest National Laboratory, Richland, WA, USA.
Charles AnsongPacific Northwest National Laboratory, Richland, WA, USA.
James P CarsonTexas Advanced Computing Center, The University of Texas at Austin, Austin, TX, USA.
Pacific Northwest National Laboratory · USThe University of Texas at Austin · USBaylor College of Medicine · USCincinnati Children's Hospital Medical Center · USRTI International · USUniversity of Alabama at Birmingham · USYale University · USHarvard University · USNeurological Research Institute · US

Funding

Center for Lung Development Imaging and OmicsU01HL122703 · NHLBI · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI ANSONG, CHARLES K, CARSON, JAMES PAUL · 2014 to 2018
$4.5M
"Lung MAP" Atlas Research CenterU01HL122642 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI POTTER, S. STEVEN, WHITSETT, JEFFREY A · 2014 to 2018
$3.9M
Tecan EVO GenePaint robotS10OD016167 · OD · BAYLOR COLLEGE OF MEDICINE · PI LJUNGBERG, CECILIA · 2013 to 2013
$215k
NHLBI NIH HHS U01 HL122642NHLBI NIH HHS U01 HL122703NIH HHS S10 OD016167
6 · The paper itself

Abstract

This data is a curated collection of visual images of gene expression patterns from the pre- and post-natal mouse lung, accompanied by associated mRNA probe sequences and RNA-Seq expression profiles. Mammalian lungs undergo significant growth and cellular differentiation before and after the transition to breathing air. Documenting normal lung development is an important step in understanding abnormal lung development, as well as the challenges faced during a preterm birth. Images in this dataset indicate the spatial distribution of mRNA transcripts for over 500 different genes that are active during lung development, as initially determined via RNA-Seq. Images were systematically acquired using high-throughput

Identifiers

PMID30596133
PMCPMC6307338
OpenAlexW2899458995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.