Evidence map›Paper›PMID 30596089›Full record

ArticleBioMed research international2018

The Potential of Fluocinolone Acetonide to Mitigate Inflammation and Lipid Accumulation in 2D and 3D Foam Cell Cultures.

Luong T H Nguyen, Aristo Muktabar, Jinkai Tang, Yee Shan Wong, Colby S Thaxton, Subbu S Venkatraman, Kee Woei Ng

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  5. Key parameters for designing robust 2D and 3D spheroid models forBioengineering & translational medicine · 2025
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  10. 3D Tumor Models in Urology.International journal of molecular sciences · 2023
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  13. Pharmaceutical biology · 2021
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  14. Recent Progress inFrontiers in cardiovascular medicine · 2021
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  15. Article
  16. Composite Hydrogels in Three-DimensionalFrontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Luong T H NguyenNanyang Technological University, School of Materials Science and Engineering, 50 Nanyang Avenue, Singapore 639798, Singapore.
Aristo MuktabarNanyang Technological University, School of Materials Science and Engineering, 50 Nanyang Avenue, Singapore 639798, Singapore.
Jinkai TangNanyang Technological University, School of Materials Science and Engineering, 50 Nanyang Avenue, Singapore 639798, Singapore.
Yee Shan WongNanyang Technological University, School of Materials Science and Engineering, 50 Nanyang Avenue, Singapore 639798, Singapore.
Colby S ThaxtonNorthwestern University, Feinberg School of Medicine, Department of Urology, Chicago, IL 60611, USA.
Subbu S VenkatramanNanyang Technological University, School of Materials Science and Engineering, 50 Nanyang Avenue, Singapore 639798, Singapore.ORCID 0000-0002-8693-1070
Kee Woei NgNanyang Technological University, School of Materials Science and Engineering, 50 Nanyang Avenue, Singapore 639798, Singapore.ORCID 0000-0002-7276-3563
Nanyang Technological University · SGNorthwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation plays an important role in all stages of atherosclerosis development. Therefore, the use of anti-inflammatory drugs could reduce the risk of major adverse cardiovascular events due to atherosclerosis. Herein, we explored the capacity of fluocinolone acetonide (FA), a glucocorticoid (GC), in modulating foam cell formation and response. Human THP-1 derived foam cells were produced using 100

Indexed as

AtherosclerosisCell Culture TechniquesCell SurvivalCytokinesDexamethasoneFluocinolone AcetonideFoam CellsGlucocorticoidsHumansInflammationLipid MetabolismLipidsLipoproteins, LDLMacrophagesCytokinesDexamethasoneFluocinolone AcetonideGlucocorticoidsLipidsLipoproteins, LDLoxidized low density lipoprotein

Identifiers

PMID30596089
PMCPMC6282138
OpenAlexW2900482348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.