Evidence map›Paper›PMID 30596016›Full record

ReviewPhotoacoustics2018

Photoacoustic tomography for human musculoskeletal imaging and inflammatory arthritis detection.

Janggun Jo, Chao Tian, Guan Xu, Jeffrey Sarazin, Elena Schiopu, Girish Gandikota, Xueding Wang

Open access · goldAbstract readReview
In one paragraph

Review in Photoacoustics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
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  4. Advances in Photoacoustic Imaging of Breast Cancer.Sensors (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Janggun JoDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, United States.
Chao TianCollege of Engineering Science, University of Science and Technology of China, Hefei, Anhui 230026, China.
Guan XuDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Jeffrey SarazinDivision of Rheumatology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48109, United States.
Elena SchiopuDivision of Rheumatology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48109, United States.
Girish GandikotaDepartment of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Xueding WangDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, United States.
University of Michigan–Ann Arbor · USMichigan Medicine · USUniversity of Science and Technology of China · CN

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Physiology of Inflammatory Arthritis in High ResolutionR01AR060350 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, XUEDING · 2011 to 2021
$6.0M
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NIAMS NIH HHS R01 AR060350
6 · The paper itself

Abstract

With the capability of assessing high resolution optical contrast in soft tissues, photoacoustic imaging (PAI) can offer valuable structural and functional information of human joints, and hold potential for diagnosis and treatment monitoring of inflammatory arthritis. Recent studies have demonstrated that PAI can map 2D and 3D morphology of the cartilage, synovium, vascularity, and bone tissue in human peripheral joints. Initial trials with patients affected by inflammatory arthritis have also suggested that PAI can detect the hemodynamic properties in articular tissues as well as their changes due to active inflammation. This review focuses on the recent progress in technical development of PAI for human musculoskeletal imaging and inflammation detection. PAI can provide non-invasive and non-ionizing serial measurements for monitoring of therapeutic interventions with the potential for higher sensitivity than existing imaging modalities such as ultrasound. However, further investigation is needed to validate the value of PAI in rheumatology clinical settings.

Indexed as

Human jointInflammatory arthritisPhotoacoustic tomography

Identifiers

PMID30596016
PMCPMC6306364
OpenAlexW2884481470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.