ArticleChemtexts2018
Polyoxometalates: more than a phasing tool in protein crystallography.
Article in Chemtexts, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- POMsDB: a QM derived molecular properties and parameters database for Polyoxometalates.Scientific data · 2026Article
- Polyoxometalates in environmental remediation and energy storage.Environmental science. Nano · 2026Review
- MXene electrochemical phosphate sensors.Communications engineering · 2025Article
- The Crystallography of Enzymes: A Retrospective and Beyond.Crystals · 2025Article
- Uncovering Polyoxometalate Speciation in Hydrothermal Systems by Combining Computational Simulation with X-ray Total Scattering.Journal of the American Chemical Society · 2025Article
- All-Inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Tyrosinases: a family of copper-containing metalloenzymes.Chemtexts · 2024Article
- Isoxazole analogues of dibenzazepine as possible leads against ulcers and skin disease:Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- KACS omega · 2023Article
- Regioselective protein oxidative cleavage enabled by enzyme-like recognition of an inorganic metal oxo cluster ligand.Nature communications · 2023Article
- Room temperature crystallography and X-ray spectroscopy of metalloenzymes.Methods in enzymology · 2023Article
- Selective Adsorption of Hemoglobin in Human Whole Blood with a Nickel Monosubstituted Silicotungstic Acid Hybrid.ACS omega · 2022Article
- Conformational flexibility in the zinc solute-binding protein ZnuA.Acta crystallographica. Section F, Structural biology communications · 2022Article
- Polyoxometalate Functionalized Sensors: A Review.Frontiers in chemistry · 2022Review
- Speciation of Transition-Metal-Substituted Keggin-Type Silicotungstates Affected by the Co-crystallization Conditions with Proteinase K.Inorganic chemistry · 2021Article
- Wells-Dawson phosphotungstates as mushroom tyrosinase inhibitors: a speciation study.Scientific reports · 2021Article
- Expanding the reactivity of inorganic clusters towards proteins: the interplay between the redox and hydrolytic activity of Ce(iv)-substituted polyoxometalates as artificial proteases.Chemical science · 2021Article
- Synthesis and characterization of the Anderson-Evans tungstoantimonate [NaActa crystallographica. Section C, Structural chemistry · 2021Article
- Defect {(WInorganic chemistry · 2021Article
- Interweaving Disciplines to Advance Chemistry: Applying Polyoxometalates in Biology.Inorganic chemistry · 2021Review
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Abstract
Protein crystallography is the most widely used method for determining the molecular structure of proteins and obtaining structural information on protein-ligand complexes at the atomic level. As the structure determines the functions and properties of a protein, crystallography is of immense importance for nearly all research fields related to biochemistry. However, protein crystallography suffers from some major drawbacks, whereby the unpredictability of the crystallization process represents the main bottleneck. Crystallization is still more or less a 'trial and error' based procedure, and therefore, very time and resource consuming. Many strategies have been developed in the past decades to improve or enable the crystallization of proteins, whereby the use of so-called additives, which are mostly small molecules that make proteins more amenable to crystallization, is one of the most convenient and successful methods. Most of the commonly used additives are, however, restricted to particular crystallization conditions or groups of proteins. Therefore, a more universal additive addressing a wider range of proteins and being applicable to a broad spectrum of crystallization conditions would represent a significant advance in the field of protein crystallography. In recent years, polyoxometalates (POMs) emerged as a promising group of crystallization additives due to their unique structures and properties. In this regard, the tellurium-centered Anderson-Evans polyoxotungstate [TeW
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